⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18422707 | 0.76 | CETP (0.39) | — | |
| SCHEMBL3422966 | 0.76 | CETP (0.39) | — | |
| SCHEMBL18422910 | 0.76 | CETP (0.39) | — | |
| SCHEMBL1316837 | 0.72 | — | — | |
| Chloroform SCHEMBL5313122 | 0.67 | ALDH1A1 (0.41) | — | |
| SCHEMBL1075071 | 0.67 | CETP (0.33) | — | |
| SCHEMBL26092 | 0.67 | — | — | |
| SCHEMBL14817655 | 0.67 | — | — | |
| SCHEMBL846347 | 0.67 | — | — | |
| Chloroform SCHEMBL6152248 | 0.67 | ALDH1A1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115057913-A | Preparation method of gramicidin S analogue GS-5 | 遵义医科大学珠海校区 | 2022-09-16 | — | — | CN | disclosed |
| CN-112175067-B | Preparation method of teduglutide | 深圳市星银医药有限公司 | 2022-04-15 | — | — | CN | disclosed |
| CN-111961117-B | Cyclopeptide compound and application thereof | 中山大学 | 2022-03-11 | — | — | CN | disclosed |
| CN-113651837-A | Preparation method of 3,3, 3-trifluoropropanol | 山东华安新材料有限公司 | 2021-11-16 | — | — | CN | disclosed |
| CN-112175067-A | Preparation method of teduglutide | 深圳市星银医药有限公司 | 2021-01-05 | — | — | CN | disclosed |
| CN-111732651-B | Method for preparing Somalutide through continuous flow solid phase reaction | 苏州金顶生物有限公司 | 2020-12-08 | — | — | CN | disclosed |
| CN-111961117-A | Cyclopeptide compound and application thereof | 中山大学 | 2020-11-20 | — | — | CN | disclosed |
| CN-111732651-A | Method for preparing Somalutide through continuous flow solid phase reaction | 苏州金顶生物有限公司 | 2020-10-02 | — | — | CN | disclosed |
| CN-110891593-A | NORRIN-inducible expression of genes and application thereof in treating diseases | 瑞特诺解决方案有限责任公司 | 2020-03-17 | — | — | CN | disclosed |
| CN-110072864-A | TDO2 INHIBITORS | 基因泰克公司 | 2019-07-30 | — | — | CN | disclosed |
| US-20170267725-A1 | Peptidomimetics for Treating HER2-Overexpressed Cancer | Board of Supervisors for the University of Louisiana System (US) | 2017-09-21 | — | — | US | disclosed |
| EP-0988394-B1 | COMPOSITIONS FOR THE DETECTION OF ENZYME ACTIVITY IN BIOLOGICAL SAMPLES AND METHODS OF USE THEREOF | ONCOIMMUNIN INC (US) | 2009-12-30 | — | — | EP | disclosed |
| US-7550592-B2 | Hydromorphone polymorphs | NORAMCO, INC. (US) | 2009-06-23 | — | — | US | disclosed |
| US-20060235039-A1 | Four novel forms of hydromorphone HCl identified herein as Forms B, C, D and an amorphous form; useful as analgesic agents either in combination with or as replacements for hydromorphone hydrochloride; useful as analgesic agents | NORAMCO, LLC (FORMERLY KNOWN AS NORAMCO, INC.) | 2006-10-19 | — | — | US | disclosed |
| JP-2004091368-A | HALOGEN-CONTAINING ALCOHOL AND ITS PRODUCTION METHOD | CENTRAL GLASS CO LTD | 2004-03-25 | — | — | JP | disclosed |
| WO-2004020376-A1 | HALOGENATED ALCOHOL AND PROCESS FOR PRODUCING THE SAME | CENTRAL GLASS COMPANY, LIMITED (JP) | 2004-03-11 | — | — | WO | disclosed |
| EP-0842195-A1 | PEPTIDE INHIBITORS OF FIBRONECTINE | ZENECA LIMITED (GB) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997002289-A1 | PEPTIDE INHIBITORS OF FIBRONECTINE | ZENECA LIMITED (GB) | 1997-01-23 | — | — | WO | disclosed |
| EP-0285562-B1 | SYNTHETIC RESIN | CIBA-GEIGY AG (CH) | 1993-04-28 | — | — | EP | disclosed |
| EP-0285562-A2 | Synthetic resin | CIBA-GEIGY AG (CH) | 1988-10-05 | — | — | EP | disclosed |