Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | DHFR | P00374 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13848298 | 0.84 | KCNA3 (0.42) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL4066925 | 0.82 | BCL2 (0.52) | ACMSDMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL4060757 | 0.82 | HSP90AA1 (0.43) | LMNAHSP90AA1AKR1C2HSP90AB1AKR1C3 | |
| SCHEMBL4069702 | 0.79 | HSP90AA1 (0.44) | LMNAHSP90AA1AKR1C2HSP90AB1AKR1C3 | |
| SCHEMBL4072687 | 0.79 | HSD17B10 (0.48) | ACMSDMEN1KMT2ADHFRKDM4E | |
| SCHEMBL13848090 | 0.79 | HSP90AA1 (0.46) | KDM4ELMNAHSD17B10HSP90AA1HSP90AB1 | |
| SCHEMBL13848169 | 0.78 | HSP90AA1 (0.65) | KDM4EMAPTHSP90AA1HSP90AB1 | |
| SCHEMBL71656 | 0.78 | MEN1 (0.46) | MEN1KMT2AKDM4ELMNAMCL1 | |
| SCHEMBL4065970 | 0.75 | HSP90AA1 (0.54) | LMNAHSP90AA1HSP90AB1 | |
| SCHEMBL4241557 | 0.73 | APP (0.50) | LMNAMAPTHSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |