Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.42 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.42 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 3/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13848420 | 0.86 | ROCK1 (0.43) | HSD17B10HPGDPOLBMAPTTSHR | |
| SCHEMBL13848474 | 0.84 | KCNK3 (0.51) | HPGDMAPTRAB9AHTTKDM4E | |
| SCHEMBL4068175 | 0.82 | P2RX3 (0.47) | POLBP2RX3P2RX2CD274AKR1C3 | |
| SCHEMBL4065128 | 0.80 | HSP90AA1 (0.46) | MAPTTSHRRAB9AKDM4EALDH1A1 | |
| SCHEMBL4061388 | 0.80 | P2RX3 (0.46) | HSD17B10HPGDPOLBMAPTTSHR | |
| SCHEMBL4071802 | 0.79 | P2RX3 (0.47) | P2RX3P2RX2CD274RAB9AALDH1A1 | |
| SCHEMBL4069860 | 0.79 | ACMSD (0.48) | HSD17B10HPGDMAPTFABP4LMNA | |
| SCHEMBL4064518 | 0.79 | LMNA (0.47) | CAMKK2MAPK8GSK3BRAB9ALMNA | |
| SCHEMBL4061598 | 0.76 | P2RX3 (0.62) | POLBP2RX3P2RX2DHFR | |
| SCHEMBL382778 | 0.74 | HPGD (0.55) | HSD17B10HPGDPOLBMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |