Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | UQCRB | P14927 | 2/20 | 0.43 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4922521 | 0.87 | BRD4 (0.54) | PTPN5BRD4UQCRBSERPINE1IKBKB | |
| SCHEMBL4069882 | 0.87 | BRD4 (0.42) | PTPN5BRD4UQCRBSERPINE1IKBKB | |
| SCHEMBL3957017 | 0.86 | SERPINE1 (0.54) | PTPN5BRD4UQCRBSERPINE1IKBKB | |
| SCHEMBL4071552 | 0.85 | SERPINE1 (0.44) | SERPINE1MEN1KMT2AMAPTHDAC3 | |
| SCHEMBL4077703 | 0.85 | PTPN5 (0.45) | PTPN5BRD4UQCRBSERPINE1IKBKB | |
| SCHEMBL4142667 | 0.84 | BRD4 (0.37) | PTPN5BRD4UQCRBSERPINE1IKBKB | |
| SCHEMBL4142664 | 0.84 | BRD4 (0.37) | PTPN5BRD4UQCRBSERPINE1IKBKB | |
| SCHEMBL4142596 | 0.81 | GAA (0.48) | ALDH1A1POLBMEN1KMT2ANPSR1 | |
| SCHEMBL4072961 | 0.80 | PTPN5 (0.45) | PTPN5BRD4UQCRBSERPINE1IKBKB | |
| SCHEMBL13910226 | 0.80 | SERPINE1 (0.51) | PTPN5BRD4UQCRBSERPINE1IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2036906-A1 | Azaindoles as inhibitors of soluble adenylate cyclase | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-03-18 | — | — | EP | claimed |
| EP-2036906-A1 | Azaindoles as inhibitors of soluble adenylate cyclase | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-03-18 | — | — | EP | disclosed |