Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 1/20 | 0.45 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | UQCRB | P14927 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3957017 | 0.89 | SERPINE1 (0.54) | PTPN5SERPINE1BRD4UQCRBALDH1A1 | |
| SCHEMBL4931052 | 0.87 | BRD4 (0.52) | PTPN5SERPINE1BRD4UQCRBALDH1A1 | |
| SCHEMBL4077705 | 0.87 | PTPN5 (0.41) | PTPN5SERPINE1BRD4UQCRBALDH1A1 | |
| SCHEMBL4077968 | 0.85 | SERPINE1 (0.45) | SERPINE1GPR35MAPTHDAC3HDAC11 | |
| SCHEMBL4072961 | 0.85 | PTPN5 (0.45) | PTPN5SERPINE1BRD4UQCRBALDH1A1 | |
| SCHEMBL4069878 | 0.85 | PTPN5 (0.45) | PTPN5SERPINE1BRD4UQCRBALDH1A1 | |
| SCHEMBL4139174 | 0.84 | ALDH1A1 (0.36) | PTPN5SERPINE1BRD4UQCRBALDH1A1 | |
| SCHEMBL4139170 | 0.84 | ALDH1A1 (0.36) | PTPN5SERPINE1BRD4UQCRBALDH1A1 | |
| SCHEMBL13910226 | 0.82 | SERPINE1 (0.51) | PTPN5SERPINE1BRD4UQCRBALDH1A1 | |
| SCHEMBL4142121 | 0.81 | MAP2 (0.54) | PTPN5SERPINE1BRD4UQCRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2036906-A1 | Azaindoles as inhibitors of soluble adenylate cyclase | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-03-18 | — | — | EP | claimed |
| EP-2036906-A1 | Azaindoles as inhibitors of soluble adenylate cyclase | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-03-18 | — | — | EP | disclosed |