SCHEMBL4070425

SCHEMBL4070425

CCOP(=O)(CCCCCCn1c2ccc(/C(C)=N/O)cc2c2cc([N+](=O)[O-])ccc21)OCC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.48
LMNA P02545 4/20 0.48
KDM4E B2RXH2 3/20 0.48
HPGD P15428 2/20 0.48
HTT P42858 2/20 0.48
GFER P55789 1/20 0.48
POLB P06746 1/20 0.41
ATM Q13315 1/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
SIGMAR1 Q99720 1/20 0.40
PSEN1 P49768 1/20 0.39
PSEN2 P49810 1/20 0.39
APH1B Q8WW43 1/20 0.39
NCSTN Q92542 1/20 0.39
APH1A Q96BI3 1/20 0.39
PSENEN Q9NZ42 1/20 0.39
MAPK1 P28482 1/20 0.36
CNR2 P34972 2/20 0.36
ACHE P22303 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4065144 0.96 MAPT (0.50) MAPTLMNAKDM4EHPGDHTT
SCHEMBL4062236 0.91 MAPT (0.47) MAPTLMNAKDM4EHPGDHTT
SCHEMBL4063017 0.90 MAPT (0.43) MAPTLMNAPOLBATMMEN1
SCHEMBL4062511 0.90 MAPT (0.38) MAPTLMNAKDM4EHPGDHTT
SCHEMBL4062431 0.86 MAPT (0.44) MAPTLMNAPOLBATMMEN1
SCHEMBL4070504 0.86 MAPT (0.39) MAPTLMNAKDM4EHPGDHTT
SCHEMBL4065224 0.82 MAPT (0.42) MAPTLMNAPOLBATMMEN1
SCHEMBL15930036 0.81 MAPT (0.41) MAPTLMNAPOLBATMMEN1
SCHEMBL4067854 0.80 MAPT (0.39) MAPTLMNAKDM4EHPGDHTT
SCHEMBL4070389 0.80 MAPT (0.44) MAPTLMNAPOLBATMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8168369-B2 Photoactive compound and photosensitive resin composition containing the same LG CHEM, LTD. (KR) 2012-05-01 US disclosed
US-20110318692-A1 PHOTOACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION CONTAINING THE SAME LG CHEM, LTD. (KR) 2011-12-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110318692-A1 PHOTOACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION CONTAINING THE SAME CCNT1, RFT1, SULT1A1 MAPT 96/4885LMNA 4369/4885KDM4E 1032/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.