Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 20/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL400980 | 0.94 | TNK2 (0.72) | TNK2 | |
| SCHEMBL401938 | 0.92 | TNK2 (0.65) | TNK2 | |
| Carbamic Acid SCHEMBL4063655 | 0.87 | TNK2 (0.69) | TNK2 | |
| SCHEMBL399370 | 0.87 | TNK2 (0.63) | TNK2 | |
| Carbamic Acid SCHEMBL4072218 | 0.87 | IGF1R (0.66) | TNK2 | |
| Carbamic Acid SCHEMBL4074258 | 0.85 | TNK2 (0.61) | TNK2 | |
| Carbamic Acid SCHEMBL4063229 | 0.85 | TNK2 (0.58) | TNK2 | |
| SCHEMBL400012 | 0.83 | TNK2 (0.64) | TNK2 | |
| Carbamic Acid SCHEMBL4066334 | 0.82 | TNK2 (0.54) | TNK2 | |
| SCHEMBL401819 | 0.82 | TNK2 (0.66) | TNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2168968-B1 | 6,6-bicyclic ring substituted heterobicyclic protein kinase inhibitors | OSI PHARMACEUTICALS LLC (US) | 2017-08-23 | — | — | EP | claimed |
| EP-1740591-B1 | 6,6-BICYCLIC RING SUBSTITUTED HETEROBICYCLIC PROTEIN KINASE INHIBITORS | OSI PHARM INC (US) | 2009-06-17 | — | — | EP | claimed |