SCHEMBL4070601

SCHEMBL4070601

CC(=O)CCc1cccc2ccccc12

nearest known ligand 0.63

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
IAPP P10997 1/20 0.56
MTNR1A P48039 2/20 0.55
TDP1 Q9NUW8 1/20 0.55
CDYL Q9Y232 1/20 0.54
ALDH1A1 P00352 2/20 0.51
LMNA P02545 1/20 0.51
GPR84 Q9NQS5 1/20 0.51
KDM4E B2RXH2 1/20 0.50
NQO2 P16083 1/20 0.50
ACP3 P15309 1/20 0.49
P2RX7 Q99572 1/20 0.48
HTT P42858 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
CYP1A2 P05177 2/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C19 P33261 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30258002 1.00 IAPP (0.56) IAPPMTNR1ATDP1CDYLALDH1A1
SCHEMBL6282199 0.90 MTNR1A (0.50) IAPPMTNR1ATDP1CDYLALDH1A1
SCHEMBL29137509 0.85 ACP3 (0.52) MTNR1ATDP1CDYLGPR84KDM4E
SCHEMBL7340131 0.85 TDP1 (0.58) IAPPMTNR1ATDP1CDYLGPR84
SCHEMBL31043020 0.84 IAPP (0.51) IAPPMTNR1AALDH1A1LMNAKDM4E
SCHEMBL30307853 0.83 TDP1 (0.67) MTNR1ATDP1CDYLGPR84KDM4E
SCHEMBL1566760 0.83 TDP1 (0.56) MTNR1ATDP1CDYLGPR84KDM4E
SCHEMBL1218835 0.83 TDP1 (0.67) MTNR1ATDP1CDYLGPR84KDM4E
SCHEMBL8093164 0.82 MTNR1A (0.53) MTNR1ATDP1CDYLGPR84KDM4E
SCHEMBL8400463 0.82 IAPP (0.58) IAPPMTNR1ATDP1CDYLGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109922793-A Poorly water soluble dietary supplements and methods of solubilizing pharmaceutically active agents 雅典娜股份公司 2019-06-21 CN claimed
CN-106456637-A (s)-pirlindole or its pharmaceutically acceptable salts for use in medicine 特克尼梅德医疗技术股份公司 2017-02-22 CN claimed
CN-106413714-A Pharmaceutical use of (R) -pirlindole and pharmaceutically acceptable salts thereof 特克尼梅德医疗技术股份公司 2017-02-15 CN claimed
CN-1388110-A Preparation of naphthalenebutanone with 4-substituted 2-butanone HOECHST CELANESE CORP (US) 2003-01-01 CN claimed
CN-1214668-A Preparation of nabumetone from 4-substituted 2-butanone HOECHST CELANESE CORP (US) 1999-04-21 CN claimed
CN-1079954-A The naphthalene butanone of spray chilling and its production method SMITHKLING BEECHAM PLC (GB) 1993-12-29 CN claimed
US-12521410-B2 Compounds and pharmaceutical uses thereof SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2026-01-13 US disclosed
US-20240180945-A1 COMPOUNDS AND PHARMACEUTICAL USES THEREOF SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2024-06-06 US disclosed
US-11793823-B2 Compounds and pharmaceutical uses thereof SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2023-10-24 US disclosed
US-11793823-B2 Compounds and pharmaceutical uses thereof SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2023-10-24 US disclosed
US-11793823-B2 Compounds and pharmaceutical uses thereof SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2023-10-24 US disclosed
WO-2023072971-A2 GASTRIC INHIBITORY PEPTIDE RECEPTOR LIGANDS 3B PHARMACEUTICALS GMBH (DE) 2023-05-04 WO disclosed
CN-115836062-A Compound and medical application thereof 心悦生医股份有限公司 2023-03-21 CN disclosed
WO-1998050033-A1 COX-2 SELECTIVE CARPROFEN FOR TREATING PAIN AND INFLAMMATION IN DOGS PFIZER INC. (US) 1998-11-12 WO disclosed
US-5777170-A Process for the preparation of a naphthylbutanone ARCHIMICA SPA (IT) 1998-07-07 US disclosed
EP-0822174-A1 Process for the preparation of a naphthylbutanone Archimica S.p.A. (IT) 1998-02-04 EP disclosed
CN-1117484-A Fatty acid derivatives SCOTIA HOLDINGS PLC (GB) 1996-02-28 CN disclosed
CN-1079954-A The naphthalene butanone of spray chilling and its production method SMITHKLING BEECHAM PLC (GB) 1993-12-29 CN disclosed
CN-1079954-A The naphthalene butanone of spray chilling and its production method SMITHKLING BEECHAM PLC (GB) 1993-12-29 CN disclosed
CN-1079954-A The naphthalene butanone of spray chilling and its production method SMITHKLING BEECHAM PLC (GB) 1993-12-29 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11793823-B2 Compounds and pharmaceutical uses thereof HRH4, OR10J3, CYP3A5 IAPP 3212/4885MTNR1A 1717/4885TDP1 4760/4885
US-20240180945-A1 COMPOUNDS AND PHARMACEUTICAL USES THEREOF HRH4, OR10J3, CYP3A5 IAPP 3212/4885MTNR1A 1717/4885TDP1 4760/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.