Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 1/20 | 0.44 |
| ▸ | NMT1 | P30419 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 4/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NMT2 | O60551 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4067389 | 0.91 | CYP3A4 (0.40) | IP6K1NMT1MAPTSMN1; SMN2CYP3A4 | |
| SCHEMBL1486598 | 0.87 | NMT1 (0.49) | IP6K1NMT1MAPTSMN1; SMN2TP53 | |
| SCHEMBL3869604 | 0.85 | NMT1 (0.49) | IP6K1NMT1MAPTSMN1; SMN2TP53 | |
| SCHEMBL1486510 | 0.85 | NMT1 (0.44) | IP6K1NMT1MAPTSMN1; SMN2TP53 | |
| SCHEMBL1486569 | 0.82 | NMT1 (0.50) | IP6K1NMT1MAPTCYP3A4EGFR | |
| SCHEMBL1486522 | 0.81 | NMT1 (0.46) | IP6K1NMT1MAPTSMN1; SMN2CYP3A4 | |
| SCHEMBL1486487 | 0.80 | NMT1 (0.47) | IP6K1NMT1MAPTSMN1; SMN2CYP3A4 | |
| SCHEMBL1486511 | 0.79 | NMT1 (0.44) | IP6K1NMT1MAPTSMN1; SMN2TP53 | |
| SCHEMBL1486577 | 0.79 | F2 (0.47) | MAPTSMN1; SMN2TP53CYP3A4ALDH1A1 | |
| SCHEMBL4336578 | 0.78 | POLB (0.44) | ALDH1A1LMNAKDM4EACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658076-A4 | ARYLOXY AND ARYLALKYLENEOXY SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES CO (US) | 2009-02-25 | — | — | EP | disclosed |
| EP-1658076-A1 | ARYLOXY AND ARYLALKYLENEOXY SUBSTITUTED IMIDAZOQUINOLINES | 3M Innovative Properties Company (US) | 2006-05-24 | — | — | EP | disclosed |
| WO-2005020999-A1 | ARYLOXY AND ARYLALKYLENEOXY SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-03-10 | — | — | WO | disclosed |