Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6773227 | 1.00 | TSHR (0.57) | TSHRGABRA1GABRB2LMNAHSD17B10 | |
| SCHEMBL30483161 | 1.00 | TSHR (0.57) | TSHRGABRA1GABRB2LMNAHSD17B10 | |
| SCHEMBL22383428 | 0.85 | TSHR (0.48) | TSHRGABRA1GABRB2LMNAHSD17B10 | |
| SCHEMBL8015528 | 0.85 | TSHR (0.48) | TSHRGABRA1GABRB2LMNAHSD17B10 | |
| SCHEMBL9098490 | 0.85 | BCHE (0.49) | TSHRGABRA1GABRB2LMNAHSD17B10 | |
| SCHEMBL10627436 | 0.84 | TSHR (0.45) | TSHRGABRA1GABRB2LMNAHPGD | |
| SCHEMBL10515048 | 0.83 | TSHR (0.55) | TSHRGABRA1GABRB2LMNAHSD17B10 | |
| SCHEMBL2517311 | 0.82 | TSHR (0.46) | TSHRGABRA1GABRB2LMNAHSD17B10 | |
| SCHEMBL1928791 | 0.81 | ACP3 (0.43) | TSHRLMNAHSD17B10HPGDALDH1A1 | |
| SCHEMBL10580121 | 0.81 | LMNA (0.41) | TSHRLMNAHSD17B10POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107311857-A | (2 hydroxy phenyl) butyric acid of 4 hydroxyls of R 2 and its preparation and application | 云南农业大学 | 2017-11-03 | — | — | CN | claimed |
| CN-101380317-B | Pharmaceutical composition for relieving pruritus | CAYMAN ISLAND SHANGANSHENG DEV PHARMACEUTICAL CO LTD | 2010-12-08 | — | — | CN | claimed |
| EP-2033635-A1 | Short-chain fatty acid derivatives for treating pruritus | Asan Laboratories Company (Cayman) Limited (CN) | 2009-03-11 | — | — | EP | claimed |
| CN-101380317-A | Pharmaceutical composition for relieving pruritus | CAYMAN ISLAND SHANGANSHENG DEV (CN) | 2009-03-11 | — | — | CN | claimed |
| US-20080107646-A1 | Administering phenylbutyric acid derivative and pharmaceutically acceptable carrier | Sunny Pharmtech Inc. (TW) | 2008-05-08 | — | — | US | claimed |
| US-6403646-B1 | ADMINISTERING PHENYLBUTYRIC ACID OR DERIVATIVES TO TREAT LIVER DISEASE AND EMPHYSEMA CAUSED BY PROTEASE INHIBITOR TYPE Z MUTATION; STIMULATES SECRETION WITHOUT INCREASING SYNTHESIS OF PROTEIN | PERLMUTTER DAVID H (US) | 2002-06-11 | — | — | US | claimed |
| JP-2119785-A | — | — | None | — | — | JP | disclosed |
| US-12295394-B2 | Water-soluble additive composition | SUMITOMO BAKELITE CO., LTD. (JP) | 2025-05-13 | — | — | US | disclosed |
| WO-2025025245-A1 | LIGHT-EMITTING DEVICE, PREPARATION METHOD, AND ELECTRONIC APPARATUS | 纳晶科技股份有限公司 | 2025-02-06 | — | — | WO | disclosed |
| WO-2025025244-A1 | LIGHT-EMITTING APPARATUS, PREPARATION METHOD AND ELECTRONIC DEVICE | 纳晶科技股份有限公司 | 2025-02-06 | — | — | WO | disclosed |
| CN-117777396-A | Heat-sealable aqueous resin composition and laminate | 荒川化学工业株式会社 | 2024-03-29 | — | — | CN | disclosed |
| CN-115725231-A | Water-based composition for barrier and laminate | 荒川化学工业株式会社 | 2023-03-03 | — | — | CN | disclosed |
| CN-115450067-A | Water-based oil proofing agent and oil-resistant paper | 荒川化学工业株式会社 | 2022-12-09 | — | — | CN | disclosed |
| WO-1993002037-A1 | ARYLAMIDOALKYL-N-HYDROXYUREA COMPOUNDS HAVING LIPOXYGENASE INHIBITORY ACTIVITY | ABBOTT LABORATORIES (US) | 1993-02-04 | — | — | WO | disclosed |
| JP-H02119785-A | PRODUCTION OF 2-OXO-4-PHENYLBUTYRIC ACID | TORAY IND INC | 1990-05-07 | — | — | JP | disclosed |
| US-4761420-A | CARDIOVASCULAR DISORDERS | LABORATOIRES SYNTEX S.A. (FR) | 1988-08-02 | — | — | US | disclosed |
| EP-0249245-A2 | Antihypertensive dihydropyridine derivatives | LABORATOIRES SYNTEX S.A. (FR) | 1987-12-16 | — | — | EP | disclosed |
| US-4112160-A | NITRILE RUBBER, PHENOLIC RESIN | SUMITOMO DUREZ COMPANY, LTD. (JP) | 1978-09-05 | — | — | US | disclosed |
| US-4054712-A | ELECTROGRAPHY | CANON KABUSHIKI KAISHA (JA) | 1977-10-18 | — | — | US | disclosed |
| US-4007233-A | NITRILE RUBBER, PHENOLIC RESIN | SUMITOMO DUREZ COMPANY, LTD. (JA) | 1977-02-08 | — | — | US | disclosed |