Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.55 |
| ▸ | DDO | Q99489 | 1/20 | 0.55 |
| ▸ | KIF11 | P52732 | 2/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 3/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30939503 | 1.00 | DAO (0.55) | DAODDOKIF11AOC3CYP1A2 | |
| Naphthoquinone SCHEMBL29182582 | 0.83 | DAO (0.49) | DAODDOKIF11AOC3CYP1A2 | |
| SCHEMBL8230643 | 0.80 | DAO (0.56) | DAODDOKIF11CYP1A2CYP2A6 | |
| SCHEMBL29713806 | 0.80 | DAO (0.56) | DAODDOKIF11CYP1A2CYP2A6 | |
| SCHEMBL28175224 | 0.80 | AOC3 (0.50) | AOC3ALDH1A1HPGDHSD17B10AHR | |
| SCHEMBL6206899 | 0.77 | DAO (0.53) | DAODDOKIF11CYP1A2CYP2A6 | |
| SCHEMBL10441152 | 0.77 | DAO (0.53) | DAODDOKIF11CYP1A2CYP2A6 | |
| SCHEMBL12778111 | 0.77 | DAO (0.53) | DAODDOKIF11CYP1A2CYP2A6 | |
| SCHEMBL19373476 | 0.77 | DAO (0.62) | DAODDOKIF11CYP1A2CYP2A6 | |
| SCHEMBL3632451 | 0.77 | DAO (0.53) | DAODDOAOC3FLT3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1051669-A | With the method for amino indole dyeing keratinous fibres, compositions and facilities and equipments | OREAL (FR) | 1991-05-29 | — | — | CN | claimed |
| EP-2029543-A2 | SUBSTITUTED 3-CYANOPYRIDINES AS PROTEIN KINASE INHIBITORS | Wyeth (US) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007146376-A2 | SUBSTITUTED 3-CYANOPYRIDINES AS PROTEIN KINASE INHIBITORS | WYETH (US) | 2007-12-21 | — | — | WO | disclosed |