⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5113382 | 0.75 | MEN1 (0.48) | — | |
| SCHEMBL5114084 | 0.74 | MEN1 (0.43) | — | |
| SCHEMBL5162501 | 0.73 | — | — | |
| Iodide SCHEMBL10528918 | 0.71 | HDAC8 (0.61) | — | |
| SCHEMBL755245 | 0.70 | — | — | |
| SCHEMBL6510805 | 0.70 | GPR84 (0.47) | — | |
| Formic Acid SCHEMBL31273947 | 0.69 | CYP2A6 (0.35) | — | |
| SCHEMBL9716225 | 0.67 | MEN1 (0.48) | — | |
| SCHEMBL10635570 | 0.64 | MEN1 (0.41) | — | |
| SCHEMBL4046859 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1139926-A | Pyridine derivatives as pesticides | CIBA GEIGY AG (CH) | 1997-01-08 | — | — | CN | claimed |
| EP-0737191-A1 | PYRIDINE DERIVATIVES AS PESTICIDES | Novartis AG (CH) | 1996-10-16 | — | — | EP | claimed |
| US-5512588-A | ANTIULCER AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-30 | — | — | US | claimed |
| WO-1995018123-A1 | PYRIDINE DERIVATIVES AS PESTICIDES | CIBA-GEIGY AG (CH) | 1995-07-06 | — | — | WO | claimed |
| CN-116940562-A | Acetamido-phenylbenzamide derivatives and methods of use thereof | 希华医药有限公司 | 2023-10-24 | — | — | CN | disclosed |
| US-20230312570-A1 | METHOD FOR PREPARING MORPHINAN DERIVATIVE HAVING DIARYL ETHER SKELETON USING NOVEL COPPER CATALYST | NIPPON CHEMIPHAR CO., LTD. (JP) | 2023-10-05 | — | — | US | disclosed |
| EP-4225745-A1 | ACETAMIDO-PHENYLBENZAMIDE DERIVATIVES AND METHODS OF USING THE SAME | Athenex, Inc. (US) | 2023-08-16 | — | — | EP | disclosed |
| EP-4206203-A1 | METHOD FOR PREPARING MORPHINAN DERIVATIVE HAVING DIARYL ETHER SKELETON USING NOVEL COPPER CATALYST | Nippon Chemiphar Co., Ltd. (JP) | 2023-07-05 | — | — | EP | disclosed |
| WO-2022076662-A1 | ACETAMIDO-PHENYLBENZAMIDE DERIVATIVES AND METHODS OF USING THE SAME | ATHENEX, INC. (US) | 2022-04-14 | — | — | WO | disclosed |
| US-20220106301-A1 | ACETAMIDO-PHENYLBENZAMIDE DERIVATIVES AND METHODS OF USING THE SAME | Health Hope Pharma Limited (HK) | 2022-04-07 | — | — | US | disclosed |
| CN-111447927-A | Naloxone transdermal drug delivery device and method of use thereof | 帝国制药美国公司 | 2020-07-24 | — | — | CN | disclosed |
| US-9796708-B2 | Pyrrolo [2,3-B] pyridine CDK9 kinase inhibitors | ABBVIE INC. (US) | 2017-10-24 | — | — | US | disclosed |
| WO-1992016526-A1 | THIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-01 | — | — | WO | disclosed |
| EP-0417751-A2 | New thiazole derivatives, processes for the preparation thereof and pharmaceutical compositon comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-03-20 | — | — | EP | disclosed |
| EP-0355612-A2 | Furylthiazole derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-28 | — | — | EP | disclosed |
| US-4735956-A | Certain 1,4-dihydro-2,6-di-lower hydrocarbyl-4-heterocyclic-3,5-pyridine dicarboxylates which are useful as calcium channel blockers | MERCK & CO., INC. (US) | 1988-04-05 | — | — | US | disclosed |
| US-4497808-A | N-Oxide compounds useful in the treatment of cardiovascular ailments | CIBA-GEIGY CORPORATION (US) | 1985-02-05 | — | — | US | disclosed |
| US-4002616-A | POLYESTERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-01-11 | — | — | US | disclosed |
| US-3962220-A | ONE-STEP, AROMATIC ALDEHYDES, ACETIC ACID | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-06-08 | — | — | US | disclosed |
| US-3962221-A | CONDENSATION, REDUCTION, OXIDATION | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-06-08 | — | — | US | disclosed |