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Formic Acid

Formic Acid

SCHEMBL4072062

CC(C)C(=O)c1ccc2c(c1)CCN(CC[C@H]1CC[C@H](NC(=O)[C@](Cc3cccnc3)(NC(=O)O)C(C)(C)C)CC1)CC2.O=CO

nearest known ligand 0.39

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Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ DRD2 P14416 19/20 0.39
▸ DRD3 P35462 15/20 0.39
▸ HTR2A P28223 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL4063515 0.85 DRD2 (0.42) DRD2DRD3
Formic Acid SCHEMBL5421453 0.81 DRD2 (0.41) DRD2DRD3HTR2A
SCHEMBL4065555 0.79 DRD2 (0.44) DRD2DRD3HTR2A
Formic Acid SCHEMBL4067397 0.79 DRD2 (0.45) DRD2DRD3HTR2A
Formic Acid SCHEMBL4071546 0.78 DRD2 (0.52) DRD2DRD3
Formic Acid SCHEMBL4071543 0.78 DRD2 (0.52) DRD2DRD3
SCHEMBL4065552 0.77 DRD2 (0.42) DRD2DRD3HTR2A
SCHEMBL5421460 0.76 DRD2 (0.40) DRD2DRD3HTR2A
SCHEMBL4064635 0.74 DRD2 (0.48) DRD2DRD3
SCHEMBL4064631 0.74 DRD2 (0.48) DRD2DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1725240-A4 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS GLAXO GROUP LTD (GB) 2009-03-25 — — EP claimed
EP-1725240-A1 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS GLAXO GROUP LIMITED (GB) 2006-11-29 — — EP claimed
WO-2005094834-A1 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS GLAXO GROUP LIMITED (GB) 2005-10-13 — — WO claimed
EP-1725240-A4 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS GLAXO GROUP LTD (GB) 2009-03-25 — — EP disclosed
EP-1725240-A1 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS GLAXO GROUP LIMITED (GB) 2006-11-29 — — EP disclosed
WO-2005094834-A1 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS GLAXO GROUP LIMITED (GB) 2005-10-13 — — WO disclosed