Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 20/20 | 0.42 |
| ▸ | DRD3 | P35462 | 14/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4063518 | 0.85 | DRD2 (0.46) | DRD2DRD3 | |
| SCHEMBL4065555 | 0.85 | DRD2 (0.44) | DRD2DRD3HTR2A | |
| SCHEMBL4065552 | 0.82 | DRD2 (0.42) | DRD2DRD3HTR2A | |
| SCHEMBL5421460 | 0.79 | DRD2 (0.40) | DRD2DRD3HTR2A | |
| Formic Acid SCHEMBL5421453 | 0.78 | DRD2 (0.41) | DRD2DRD3HTR2A | |
| SCHEMBL4064109 | 0.75 | HRH2 (0.52) | DRD2DRD3HTR2A | |
| SCHEMBL4064111 | 0.75 | HRH2 (0.52) | DRD2DRD3HTR2A | |
| Formic Acid SCHEMBL4067397 | 0.75 | DRD2 (0.45) | DRD2DRD3HTR2A | |
| SCHEMBL4064631 | 0.74 | DRD2 (0.48) | DRD2DRD3 | |
| SCHEMBL4064635 | 0.74 | DRD2 (0.48) | DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1725240-A4 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LTD (GB) | 2009-03-25 | — | — | EP | claimed |
| EP-1725240-A1 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2006-11-29 | — | — | EP | claimed |
| WO-2005094834-A1 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2005-10-13 | — | — | WO | claimed |
| EP-1725240-A4 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LTD (GB) | 2009-03-25 | — | — | EP | disclosed |
| EP-1725240-A1 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2006-11-29 | — | — | EP | disclosed |
| WO-2005094834-A1 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2005-10-13 | — | — | WO | disclosed |