Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.64 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9999700 | 0.86 | ESR1 (0.45) | ESR1ESR2PDK2ALDH1A1CYP2C19 | |
| SCHEMBL13816609 | 0.85 | ESR1 (0.44) | ESR1ESR2MEN1KMT2APOLB | |
| SCHEMBL10299747 | 0.83 | ESR1 (0.42) | ESR1ESR2L3MBTL1ALOX15PDK2 | |
| SCHEMBL899482 | 0.83 | ESR1 (0.68) | ESR1ESR2MEN1KMT2AMAPT | |
| SCHEMBL3155226 | 0.82 | ESR1 (0.41) | ESR1ESR2MEN1KMT2AMAPT | |
| SCHEMBL31276113 | 0.81 | ESR1 (0.64) | ESR1ESR2MEN1KMT2AMAPT | |
| SCHEMBL5147567 | 0.79 | ESR1 (0.40) | ESR1ESR2MEN1KMT2AMAPT | |
| SCHEMBL4760269 | 0.78 | NQO2 (0.41) | ESR1ESR2MEN1KMT2AMAPT | |
| SCHEMBL899538 | 0.78 | ESR1 (0.60) | ESR1ESR2MEN1KMT2AMAPT | |
| SCHEMBL70957 | 0.78 | ESR1 (1.00) | ESR1ESR2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009058396-A1 | NEGATIVE BIREFRINGENT OPTICAL FILMS WITH FLAT OR REVERSED BIREFRINGENCE WAVELENGTH DISPERSIONS FOR LIQUID CRYSTAL DISPLAYS | AKRON POLYMER SYSTEMS INC. (US) | 2009-05-07 | — | — | WO | disclosed |
| WO-2009058396-A1 | NEGATIVE BIREFRINGENT OPTICAL FILMS WITH FLAT OR REVERSED BIREFRINGENCE WAVELENGTH DISPERSIONS FOR LIQUID CRYSTAL DISPLAYS | AKRON POLYMER SYSTEMS INC. (US) | 2009-05-07 | — | — | WO | disclosed |