Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.68 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18648071 | 0.88 | TRPA1 (0.52) | ESR1ESR2TDP1TP53MAPT | |
| SCHEMBL13080604 | 0.87 | ESR1 (0.52) | ESR1ESR2TDP1TP53MAPT | |
| SCHEMBL12924695 | 0.86 | ESR1 (0.50) | ESR1ESR2TDP1TP53MAPT | |
| SCHEMBL2675832 | 0.86 | ESR1 (0.68) | ESR1ESR2TDP1TP53MAPT | |
| SCHEMBL31276113 | 0.83 | ESR1 (0.64) | ESR1ESR2TDP1TP53MAPT | |
| SCHEMBL4072602 | 0.83 | ESR1 (0.64) | ESR1ESR2TDP1TP53MAPT | |
| SCHEMBL899618 | 0.82 | ESR1 (0.45) | ESR1ESR2TDP1TP53MEN1 | |
| SCHEMBL900028 | 0.81 | ESR1 (0.45) | ESR1ESR2TDP1TP53MAPT | |
| SCHEMBL899538 | 0.81 | ESR1 (0.60) | ESR1ESR2TDP1TP53MAPT | |
| SCHEMBL900305 | 0.81 | ESR1 (0.45) | ESR1ESR2TDP1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012042058-A1 | IMPACT RESISTANCE MODIFIERS FOR EPOXY RESIN COMPOSITIONS | SIKA TECHNOLOGY AG (CH) | 2012-04-05 | — | — | WO | disclosed |
| US-20080027244-A1 | Method for Manufacturing Aromatic Dicarboxylic Acid | JFE CHEMICAL CORPORATION (JP) | 2008-01-31 | — | — | US | disclosed |
| US-20070255075-A1 | Aromatic Diamine And Method For Manufacturing Same | JFE CHEMICAL CORPORATION (JP) | 2007-11-01 | — | — | US | disclosed |
| EP-1834943-A1 | PROCESS FOR PRODUCING AROMATIC DICARBOXYLIC ACID | JFE Chemical Corporation (JP) | 2007-09-19 | — | — | EP | disclosed |
| EP-1803705-A1 | AROMATIC DIAMINE AND PROCESS FOR PRODUCING THE SAME | JFE Chemical Corporation (JP) | 2007-07-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027244-A1 | Method for Manufacturing Aromatic Dicarboxylic Acid | DDC, PAH, ALDH7A1 | ESR1 4756/4885ESR2 4811/4885TDP1 828/4885 |
| US-20070255075-A1 | Aromatic Diamine And Method For Manufacturing Same | AOC1, DDC, PADI1 | ESR1 1381/4885ESR2 2044/4885TDP1 751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.