SCHEMBL40729

SCHEMBL40729

[CH2]S(C)(=O)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28947788 0.94
SCHEMBL19838028 0.78
Dimethyl Sulfone SCHEMBL2203884 0.75
SCHEMBL31186 0.75
SCHEMBL2339270 0.72
Dimethyl Sulfone SCHEMBL19382 0.72
Dimethyl Sulfone SCHEMBL169867 0.72 KDM4E (1.00)
SCHEMBL1108303 0.67
SCHEMBL8275257 0.67
Ethylene SCHEMBL2533442 0.67 CA2 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4478 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118146285-A Modified nucleoside, preparation method thereof, oligonucleotide prepared from modified nucleoside and application of oligonucleotide 北京悦康科创医药科技股份有限公司 2024-06-07 CN claimed
US-20240101549-A1 N-(2-(4-CYANOTHIAZOLIDIN-3-YL)-2-OXOETHYL)-QUINOLINE-4-CARBOXAMIDES ASTRAZENECA AB (SE) 2024-03-28 US claimed
CN-115135659-B Morpholine derivative, and preparation method and application thereof 深圳微芯生物科技股份有限公司 2024-03-12 CN claimed
WO-2024033388-A1 BICYCLIC TETRAHYDROTHIAZEPINE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2024-02-15 WO claimed
US-20240051954-A1 PYRROLO[3,2-B]PYRIDINE DERIVATIVES USEFUL IN TREATING CONDITIONS ASSOCIATED WITH CGAS NOVARTIS PHARMA AG (CH) 2024-02-15 US claimed
WO-2024022286-A1 MACROCYCLIC EGFR INHIBITOR, AND PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF 上海和誉生物医药科技有限公司 2024-02-01 WO claimed
US-20230416238-A1 N-[(1,3-BENZOXAZOL-2-YL)-HETEROCYCLE]AMIDE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION HOFFMANN-LA ROCHE INC. (US) 2023-12-28 US claimed
US-20230348516-A1 YKL-40 INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS MOLECURE S.A. (PL) 2023-11-02 US claimed
EP-4269400-A1 YKL-40 INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS Molecure SA (PL) 2023-11-01 EP claimed
EP-4267571-A1 PYRROLO[3,2-B]PYRIDINE DERIVATIVES USEFUL IN TREATING CONDITIONS ASSOCIATED WITH CGAS Novartis AG (CH) 2023-11-01 EP claimed
EP-0023385-A1 Ethanamine derivatives, their preparation and use in pharmaceutical compositions BEECHAM GROUP PLC (GB) 1981-02-04 EP claimed
EP-0021636-A1 Secondary amines, their preparation and use in pharmaceutical compositions BEECHAM GROUP PLC (GB) 1981-01-07 EP claimed
US-4235892-A AROMATIC ANTIBIOTICS Schering Corporation, Patent Dept. (US) 1980-11-25 US claimed
EP-0014437-A2 Novel 1-aryl-2-acylamido-3-fluoro-1-propanols, their preparation and pharmaceutical compositions containing them SCHERING CORPORATION (US) 1980-08-20 EP claimed
US-4215119-A VASODILATORS, ANTIDEPRESSANTS BOEHRINGER INGELHEIM GMBH (DE) 1980-07-29 US claimed
EP-0007470-A2 Cephem compounds, processes for their preparation and pharmaceutical compositions containing them FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1980-02-06 EP claimed
EP-0006735-A1 Secondary amines, their preparation, pharmaceutical compositions containing them and their use BEECHAM GROUP PLC (GB) 1980-01-09 EP claimed
US-4154829-A ANTIDEPRESSANT, VASODILATION BOEHRINGER INGELHEIM GMBH (DE) 1979-05-15 US claimed
US-4141890-A FIBER-REACTIVE CIBA-GEIGY CORPORATION (US) 1979-02-27 US claimed
US-3952101-A BETA ADRENERGIC STIMULANT SMITHKLINE CORPORATION (US) 1976-04-20 US claimed