Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | UQCRB | P14927 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4067709 | 0.93 | SERPINE1 (0.49) | SERPINE1BRD4UQCRBALDH1A1POLB | |
| SCHEMBL4404817 | 0.91 | FABP1 (0.44) | SERPINE1UQCRBPOLBMEN1KMT2A | |
| SCHEMBL4392130 | 0.88 | SERPINE1 (0.47) | SERPINE1BRD4UQCRBALDH1A1POLB | |
| SCHEMBL4067259 | 0.87 | SERPINE1 (0.46) | SERPINE1BRD4UQCRBALDH1A1POLB | |
| SCHEMBL4142121 | 0.86 | MAP2 (0.54) | SERPINE1BRD4UQCRBALDH1A1POLB | |
| SCHEMBL3957017 | 0.84 | SERPINE1 (0.54) | SERPINE1BRD4UQCRBALDH1A1POLB | |
| SCHEMBL4072140 | 0.84 | SERPINE1 (0.42) | SERPINE1BRD4ALDH1A1POLBMEN1 | |
| SCHEMBL4072264 | 0.84 | EDNRB (0.46) | SERPINE1MEN1KMT2ANPSR1PTPN5 | |
| SCHEMBL13910226 | 0.83 | SERPINE1 (0.51) | SERPINE1BRD4UQCRBALDH1A1POLB | |
| SCHEMBL4070333 | 0.83 | FABP1 (0.45) | SERPINE1UQCRBALDH1A1POLBPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2036906-A1 | Azaindoles as inhibitors of soluble adenylate cyclase | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-03-18 | — | — | EP | claimed |
| EP-2036906-A1 | Azaindoles as inhibitors of soluble adenylate cyclase | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-03-18 | — | — | EP | disclosed |