Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 1/20 | 0.46 |
| ▸ | EDNRA | P25101 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.45 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.45 |
| ▸ | ACLY | P53396 | 1/20 | 0.44 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 3/20 | 0.41 |
| ▸ | USP8 | P40818 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4067709 | 0.91 | SERPINE1 (0.49) | PTPN5MAPTMEN1LMNAHTT | |
| SCHEMBL4070333 | 0.90 | FABP1 (0.45) | ACLYSERPINE1 | |
| SCHEMBL4069651 | 0.89 | SERPINE1 (0.52) | KITMAPTSERPINE1 | |
| SCHEMBL4397313 | 0.89 | HIF1A (0.47) | EDNRBEDNRAPTPN2PTPN1PTPN5 | |
| SCHEMBL4072263 | 0.86 | ACLY (0.48) | EDNRBEDNRAPTPN2PTPN1PTPN5 | |
| SCHEMBL4073082 | 0.84 | SERPINE1 (0.48) | EDNRAPTPN5MAPTMEN1LMNA | |
| SCHEMBL4404817 | 0.83 | FABP1 (0.44) | KITBRAFMAPTMEN1KMT2A | |
| SCHEMBL4133133 | 0.81 | HIF1A (0.53) | EDNRBEDNRAPTPN2PTPN1PTPN5 | |
| SCHEMBL4067259 | 0.81 | SERPINE1 (0.46) | EDNRBEDNRAPTPN5USP2MEN1 | |
| SCHEMBL4392130 | 0.81 | SERPINE1 (0.47) | EDNRAPTPN5MAPTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2036906-A1 | Azaindoles as inhibitors of soluble adenylate cyclase | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-03-18 | — | — | EP | claimed |
| EP-2036906-A1 | Azaindoles as inhibitors of soluble adenylate cyclase | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-03-18 | — | — | EP | disclosed |