Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 1/20 | 0.63 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.63 |
| ▸ | EGFR | P00533 | 6/20 | 0.33 |
| ▸ | PRCP | P42785 | 4/20 | 0.32 |
| ▸ | CNR1 | P21554 | 5/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 4/20 | 0.30 |
| ▸ | KRAS | P01116 | 2/20 | 0.30 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4883051 | 0.77 | CSNK1D (1.00) | CSNK1DCSNK1G2EGFRPRCP | |
| SCHEMBL4073323 | 0.70 | CSNK1D (0.39) | CSNK1DCSNK1G2 | |
| SCHEMBL14112087 | 0.62 | CSNK1D (0.67) | CSNK1DCSNK1G2 | |
| SCHEMBL27764392 | 0.60 | CSNK1D (0.52) | CSNK1DCSNK1G2 | |
| SCHEMBL14112311 | 0.59 | CSNK1D (0.64) | CSNK1DCSNK1G2CNR1CNR2 | |
| SCHEMBL3945891 | 0.59 | LPAR2 (0.38) | CNR1CNR2 | |
| SCHEMBL4882005 | 0.59 | CSNK1D (0.62) | CSNK1DCSNK1G2 | |
| SCHEMBL14208796 | 0.59 | CSNK1D (0.55) | CSNK1DCSNK1G2 | |
| SCHEMBL4881149 | 0.57 | CSNK1D (0.55) | CSNK1DCSNK1G2 | |
| SCHEMBL2160101 | 0.56 | CCR1 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099454-A2 | AMINOPYRROLIDINES AS CHEMOKINE RECEPTOR ANTAGONISTS | Abbott Laboratories (US) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008060621-A2 | AMINOPYRROLIDINES AS CHEMOKINE RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2008-05-22 | — | — | WO | disclosed |