SCHEMBL407338

SCHEMBL407338

O=C=Nc1ccc2ccccc2c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.52
NPC1 O15118 5/20 0.52
RAB9A P51151 5/20 0.52
KMT2A Q03164 5/20 0.52
HSP90AA1 P07900 3/20 0.52
TDP1 Q9NUW8 2/20 0.50
MAPK1 P28482 1/20 0.50
HTR3E A5X5Y0 2/20 0.48
HTR3B O95264 2/20 0.48
HTR3A P46098 2/20 0.48
HTR3D Q70Z44 2/20 0.48
HTR3C Q8WXA8 2/20 0.48
CYP3A4 P08684 3/20 0.47
TRPA1 O75762 1/20 0.47
TSHR P16473 1/20 0.43
KDM4E B2RXH2 1/20 0.43
POLB P06746 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.42
GAA P10253 1/20 0.42
SIGMAR1 Q99720 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31682271 1.00 MEN1 (0.52) MEN1NPC1RAB9AKMT2AHSP90AA1
SCHEMBL3714131 0.94 TDP1 (0.48) MEN1NPC1RAB9AKMT2AHSP90AA1
SCHEMBL108863 0.91 TDP1 (0.58) MEN1NPC1RAB9AKMT2AHSP90AA1
SCHEMBL29642672 0.89 TDP1 (0.56) MEN1NPC1RAB9AKMT2AHSP90AA1
SCHEMBL542795 0.89 TDP1 (0.56) MEN1NPC1RAB9AKMT2AHSP90AA1
SCHEMBL9229837 0.86 TDP1 (0.54) MEN1NPC1RAB9AKMT2AHSP90AA1
SCHEMBL11227393 0.86 TDP1 (0.54) MEN1NPC1RAB9AKMT2AHSP90AA1
SCHEMBL381627 0.82 MEN1 (0.55) MEN1NPC1RAB9AKMT2AHSP90AA1
SCHEMBL29355266 0.82 MEN1 (0.55) MEN1NPC1RAB9AKMT2AHSP90AA1
SCHEMBL11209504 0.81 MAOA (0.45) MEN1NPC1RAB9AKMT2AHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 638 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3581600-B1 RESIN LENS AND PREPARATION METHOD THEREFOR EFIRM NEW MAT CO LTD (CN) 2025-01-08 EP claimed
CN-118980768-A Glyceride and analysis method of isomer thereof 暨南大学 2024-11-19 CN claimed
CN-118772206-A Isocyanorhodium (I) zwitterionic complex, preparation method thereof, micelle, nano diagnosis and treatment probe and anticancer drug 兰州大学 2024-10-15 CN claimed
CN-115434147-B Anti-falling Mao Shanhu velvet fabric and preparation method thereof 菏泽市源林川服饰有限公司 2024-02-13 CN claimed
EP-4288443-A1 MODIFIED GUAYULE RESIN PRODUCT AND RELATED PROCESSES BRIDGESTONE CORPORATION (JP) 2023-12-13 EP claimed
CN-114538857-B Environment-friendly carbonization-resistant cement concrete 广东粤皖混凝土有限公司 2023-04-28 CN claimed
CN-114380558-B Green high-performance cement concrete and preparation method thereof 贵州亚泰远通电业有限公司 2022-12-16 CN claimed
CN-115434147-A Anti-hair-falling coral fleece fabric and preparation method thereof 菏泽市源林川服饰有限公司 2022-12-06 CN claimed
WO-2022170364-A1 MODIFIED GUAYULE RESIN PRODUCT AND RELATED PROCESSES BRIDGESTONE CORPORATION (JP) 2022-08-11 WO claimed
CN-114538857-A Green anti-carbonization cement concrete 贵州大兴旺新材料科技有限公司 2022-05-27 CN claimed
CN-112341641-A Double-network particle gel and preparation method thereof 南京工业大学 2021-02-09 CN claimed
CN-107176925-B Synthesis method of polysubstituted imidazoline-2, 4-diketone compound 湖北科技学院 2020-04-28 CN claimed
CN-108546325-A A kind of resin lens and preparation method thereof 山东益丰生化环保股份有限公司 2018-09-18 CN claimed
CN-107176925-A A kind of synthetic method of the cyclohexadione compounds of polysubstituted imidazoline 2,4 湖北科技学院 2017-09-19 CN claimed
CN-106749378-A A kind of dynamics enhancement type polysilsesquioxane aerogel and preparation method thereof 淮阴工学院 2017-05-31 CN claimed
CN-103304446-B Derivatization method of optically active phenylacetylene compound UNIV HARBIN ENG 2015-02-25 CN claimed
CN-103304446-A Derivatization method of optically active phenylacetylene compound UNIV HARBIN ENG 2013-09-18 CN claimed
WO-2010112946-A1 ADAMANTANE BISUREA DERIVATIVES, METHOD OF PREPARATION AND APPLICATION IN ANION SENSING RUDJER BOSKOVIC INSTITUTE (HR) 2010-10-07 WO claimed
US-6534618-B1 Dehydration using isocyanate compound CORNING INCORPORATED 2003-03-18 US claimed
US-3940246-A Sublimation transfer and isocyanate fixation of amino- or hydroxy-containing dyestuffs and transfer sheets therefor CIBA-GEIGY AG (CH) 1976-02-24 US claimed