Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.45 |
| ▸ | PPARA | Q07869 | 9/20 | 0.45 |
| ▸ | PPARD | Q03181 | 3/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4084583 | 1.00 | PPARG (0.45) | PPARGPPARAPPARDMTNR1AMTNR1B | |
| SCHEMBL4074513 | 0.91 | PPARA (0.56) | PPARGPPARAPPARDFFAR1 | |
| SCHEMBL4795129 | 0.90 | MTNR1A (0.43) | PPARGPPARAMTNR1AMTNR1BFFAR1 | |
| SCHEMBL4073135 | 0.90 | MTNR1A (0.43) | PPARGPPARAMTNR1AMTNR1BFFAR1 | |
| SCHEMBL4074518 | 0.89 | PPARA (0.53) | PPARGPPARAPPARDFFAR1 | |
| SCHEMBL4075619 | 0.89 | PPARA (0.53) | PPARGPPARAPPARDFFAR1 | |
| Water SCHEMBL5158847 | 0.88 | PPARA (0.53) | PPARGPPARAPPARDFFAR1 | |
| SCHEMBL13656062 | 0.88 | SLC2A1 (0.43) | MTNR1AMTNR1BFFAR1FAAHHIF1A | |
| Arginine SCHEMBL4073126 | 0.87 | MTNR1A (0.38) | PPARGPPARAPPARDMTNR1AMTNR1B | |
| Arginine SCHEMBL4085067 | 0.87 | MTNR1A (0.38) | PPARGPPARAPPARDMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598293-B2 | Compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S LABORATORIES, INC. (US) | 2009-10-06 | — | — | US | claimed |
| EP-1453795-A2 | ESTERS AND AMIDES AS PPAR-ALPHA AGONISTS | Dr. Reddy's Laboratories Ltd. (IN) | 2004-09-08 | — | — | EP | claimed |
| WO-2003048116-A2 | ESTERS AND AMIDES AS PPAR-ALPHA AGONISTS ____________ | DR. REDDY'S LABORATORIES LTD. (IN) | 2003-06-12 | — | — | WO | claimed |