Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13907820 | 0.83 | TDP1 (0.47) | KMT2AACACBNPC1RAB9ATDP1 | |
| SCHEMBL4064265 | 0.80 | ACACB (0.40) | KMT2AMEN1HTTGFERHSD17B10 | |
| SCHEMBL24718925 | 0.77 | KMT2A (0.55) | KMT2AMEN1HTTGFERHSD17B10 | |
| SCHEMBL3963897 | 0.77 | KMT2A (0.43) | KMT2AMEN1HTTGFERHSD17B10 | |
| SCHEMBL697595 | 0.69 | KMT2A (0.60) | KMT2AMEN1HTTGFERHSD17B10 | |
| SCHEMBL17473134 | 0.69 | KMT2A (0.54) | KMT2AMEN1HTTGFERHSD17B10 | |
| SCHEMBL1286093 | 0.68 | KDR (0.44) | KMT2AMEN1GFERHSD17B10ACACB | |
| SCHEMBL21648257 | 0.68 | MAOB (0.71) | KMT2AMEN1HTTMAOBMAOA | |
| SCHEMBL3352484 | 0.68 | ACACB (0.43) | KMT2AMEN1ACACBKDM4ELMNA | |
| SCHEMBL4064262 | 0.68 | ALDH1A1 (0.44) | KMT2AMEN1HSD17B10ACACBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034029-A2 | 1-SUBSTITUTED 4-HETEROCYCLYLPIPERIDINES FOR USE AS CGRP ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-03-19 | — | — | WO | disclosed |