SCHEMBL4074583

SCHEMBL4074583

C=Cc1ccc(-c2ccccc2-c2ccccc2)cc1-c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FLT3 P36888 2/20 0.39
PELI1 Q96FA3 1/20 0.38
APP P05067 1/20 0.38
PTGS2 P35354 1/20 0.37
MEN1 O00255 1/20 0.37
APAF1 O14727 1/20 0.37
NPC1 O15118 1/20 0.37
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
THRB P10828 1/20 0.37
XBP1 P17861 1/20 0.37
PTBP1 P26599 1/20 0.37
HTT P42858 1/20 0.37
RAB9A P51151 1/20 0.37
GALK1 P51570 1/20 0.37
BLM P54132 1/20 0.37
SMAD3 P84022 1/20 0.37
KMT2A Q03164 1/20 0.37
ATM Q13315 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4071711 0.90 MEN1 (0.42) FLT3PELI1MEN1APAF1NPC1
SCHEMBL32662830 0.87 FLT3 (0.47) FLT3PTGS2BACE1ALDH1A1HSD17B10
Styrene SCHEMBL9476487 0.84 ALDH1A1 (0.56) PELI1PTGS2ALDH1A1CYP2A6TSHR
SCHEMBL4201594 0.81 ALDH1A1 (0.43) FLT3PTGS2BACE1ALDH1A1HSD17B10
SCHEMBL8758641 0.81 ALDH1A1 (0.43) FLT3ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL29418124 0.81 ALDH1A1 (0.46) FLT3BACE1ALDH1A1HSD17B10HPGD
SCHEMBL76904 0.81 ALDH1A1 (0.46) FLT3BACE1ALDH1A1HSD17B10HPGD
SCHEMBL28089479 0.80 BACE1 (0.48) PELI1APPMEN1LMNAMAPT
SCHEMBL7569813 0.80 ALDH1A1 (0.44) FLT3PELI1PTGS2MEN1NPC1
Water SCHEMBL8470277 0.79 ALDH1A1 (0.44) FLT3BACE1ALDH1A1HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2019120-B1 BLOCK COPOLYMERS NIPPON SODA CO (JP) 2016-04-13 EP disclosed
US-8193285-B2 Block copolymers NIPPON SODA CO., LTD. (JP) 2012-06-05 US disclosed
US-20090253867-A1 BLOCK COPOLYMERS NIPPON SODA CO., LTD. (JP) 2009-10-08 US disclosed
EP-2019120-A1 BLOCK COPOLYMERS Nippon Soda Co., Ltd. (JP) 2009-01-28 EP disclosed