Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4076560 | 0.90 | NR3C1 (0.68) | NR3C1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL476767 | 0.82 | NR3C1 (0.68) | NR3C1 | |
| SCHEMBL476781 | 0.81 | NR3C1 (0.88) | NR3C1 | |
| SCHEMBL476750 | 0.81 | NR3C1 (0.80) | NR3C1 | |
| SCHEMBL476796 | 0.80 | NR3C1 (0.66) | NR3C1 | |
| SCHEMBL476722 | 0.80 | NR3C1 (0.84) | NR3C1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL476774 | 0.78 | NR3C1 (1.00) | NR3C1 | |
| SCHEMBL476753 | 0.78 | NR3C1 (0.90) | NR3C1 | |
| SCHEMBL476758 | 0.77 | NR3C1 (0.77) | NR3C1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL476723 | 0.77 | NR3C1 (0.84) | NR3C1CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081910-A1 | NOVEL COMPOUNDS | Glaxo Group Limited (GB) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008043789-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2008-04-17 | — | — | WO | disclosed |