Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 7/20 | 0.49 |
| ▸ | FAAH | O00519 | 2/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.49 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMO | Q99835 | 1/20 | 0.43 |
| ▸ | APOB | P04114 | 2/20 | 0.43 |
| ▸ | MTTP | P55157 | 2/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3288509 | 0.95 | NTRK1 (0.50) | EPHX2NTRK1KCNH2NTRK3NTRK2 | |
| SCHEMBL3288520 | 0.94 | NTRK1 (0.49) | EPHX2FAAHNTRK1KCNH2NTRK3 | |
| SCHEMBL3289872 | 0.93 | NTRK1 (0.51) | EPHX2NTRK1KCNH2NTRK3NTRK2 | |
| SCHEMBL3293472 | 0.93 | NTRK1 (0.51) | EPHX2NTRK1KCNH2NTRK3NTRK2 | |
| SCHEMBL3291768 | 0.93 | NTRK1 (0.50) | EPHX2NTRK1KCNH2NTRK3NTRK2 | |
| SCHEMBL3292493 | 0.92 | POLB (0.51) | EPHX2FAAHNTRK1KCNH2NTRK3 | |
| SCHEMBL3295229 | 0.91 | NPC1 (0.50) | EPHX2NTRK1KCNH2NTRK3NTRK2 | |
| SCHEMBL3290110 | 0.91 | NTRK1 (0.48) | EPHX2NTRK1KCNH2NTRK3NTRK2 | |
| SCHEMBL3290024 | 0.91 | NTRK1 (0.48) | EPHX2NTRK1KCNH2NTRK3NTRK2 | |
| SCHEMBL3345028 | 0.90 | CFD (0.47) | EPHX2NTRK1KCNH2NTRK3NTRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1753721-B1 | AROYL-O-PIPERIDINE DERIVATIVES FOR THE TREATMENT OF DIABETES-RELATED PROBLEMS | MERCK PATENT GMBH (DE) | 2009-08-05 | — | — | EP | claimed |