SCHEMBL4075219

SCHEMBL4075219

O=C(O)C(Cl)(Cl)C(Cl)=C(Cl)Cl

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.44
TP53 P04637 1/20 0.44
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11365546 0.97 ALDH1A1 (0.42) ALDH1A1TP53TSHR
SCHEMBL11365538 0.78 ALDH1A1 (0.32) ALDH1A1TP53TSHR
SCHEMBL6063706 0.75
SCHEMBL28601158 0.72 ALDH1A1 (0.57) ALDH1A1TP53TSHR
SCHEMBL14637692 0.72 ALDH1A1 (0.57) ALDH1A1TP53TSHR
SCHEMBL11795128 0.72 ALDH1A1 (0.57) ALDH1A1TP53TSHR
Bicarbonate SCHEMBL6897373 0.71 ALDH1A1 (0.47) ALDH1A1TP53TSHR
SCHEMBL23829824 0.69
SCHEMBL1940539 0.65
Tetrachloroethylene SCHEMBL1405452 0.65 ALDH1A1 (0.47) ALDH1A1TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104854117-A Process for the synthesis of N-phosphonomethyliminodiacetic acid STRAITMARK HOLDING AG 2015-08-19 CN disclosed
CN-104812766-A Method for synthesis of aminoalkylenephosphonic acid STRAITMARK HOLDING AG 2015-07-29 CN disclosed
CN-104812764-A Process for the synthesis of N- (phosphonomethyl) glycine STRAITMARK HOLDING AG 2015-07-29 CN disclosed
US-7514386-B2 Chlorinated promoters for vanadium-based polymerization catalysts POLIMERI EUROPA S.P.A. (IT) 2009-04-07 US disclosed
US-20050274928-A1 Chlorinated promoters for vanadium-based polymerization catalysts POLIMERI EUROPA S.P.A. (IT) 2005-12-15 US disclosed
EP-1600462-A2 Chlorinated promoters for vanadium-based polymerization catalysts Polimeri Europa S.p.A. (IT) 2005-11-30 EP disclosed
US-4361686-A Preparation of copolymers of ethylene with at least one other 1-monoolefin and an optional unconjugated diene CHEMISCHE WERKE HUELS, AKTIENGESELLSCHAFT (DE) 1982-11-30 US disclosed
US-4181790-A A 2,3,4,4-TETRACHLORO-3-BUTENOATE Chemische Werke Huels, Aktiengellschaft (DE) 1980-01-01 US disclosed
US-4175095-A Process for the manufacture of pentachlorovinylacetyl chloride CHEMISCHE WERKE HULS, A.G. (DE) 1979-11-20 US disclosed