Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1466234 | 0.90 | MEN1 (0.52) | MEN1KMT2AKDM1ALMNAALOX5 | |
| SCHEMBL1463887 | 0.87 | CNR2 (0.48) | MAPTSMN1; SMN2RAB9ACNR2NPC1 | |
| SCHEMBL1465579 | 0.79 | ALDH1A1 (0.50) | MAPTCNR2HPGDALDH1A1HSD17B10 | |
| SCHEMBL4073631 | 0.78 | MEN1 (0.40) | MEN1KMT2AKDM1ALMNAALOX5 | |
| SCHEMBL1465768 | 0.77 | CNR2 (0.59) | MEN1KMT2AKDM1ALMNAALOX5 | |
| SCHEMBL1465943 | 0.76 | DHODH (0.55) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL1466154 | 0.73 | MEN1 (0.53) | MEN1KMT2AKDM1ALMNAMAPT | |
| SCHEMBL1463901 | 0.73 | CNR2 (0.59) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL1465767 | 0.71 | ALDH1A1 (0.55) | CNR2ALDH1A1PKMNPSR1CNR1 | |
| SCHEMBL3960775 | 0.71 | CNR2 (0.42) | MAPTCNR2HPGDALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | claimed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | claimed |