Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24810529 | 0.82 | CYP1A2 (0.53) | ALDH1A1CYP1A2TSHRUSP2LMNA | |
| SCHEMBL3402007 | 0.82 | ALDH1A1 (0.57) | ALDH1A1CYP1A2TSHRUSP2LMNA | |
| SCHEMBL16312791 | 0.80 | CYP1A2 (0.55) | ALDH1A1CYP1A2TSHRUSP2LMNA | |
| SCHEMBL11937857 | 0.79 | ALDH1A1 (0.59) | ALDH1A1CYP1A2TSHRUSP2LMNA | |
| SCHEMBL13563890 | 0.78 | ALDH1A1 (0.52) | ALDH1A1CYP1A2TSHRUSP2LMNA | |
| SCHEMBL27685887 | 0.77 | CYP1A2 (0.52) | ALDH1A1CYP1A2TSHRUSP2LMNA | |
| SCHEMBL2920990 | 0.76 | CYP1A2 (0.59) | ALDH1A1CYP1A2TSHRUSP2LMNA | |
| SCHEMBL244829 | 0.76 | TSHR (0.50) | ALDH1A1CYP1A2TSHRUSP2LMNA | |
| SCHEMBL528544 | 0.76 | CYP1A2 (0.55) | ALDH1A1CYP1A2TSHRUSP2LMNA | |
| SCHEMBL337085 | 0.75 | ALDH1A1 (0.70) | ALDH1A1CYP1A2TSHRUSP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728866-A | Process for the preparation of (+)-(1R) -cis-3-oxo-2-pentyl-1-cyclopentaneacetic acid | FIRMENICH SA (CH) | 1998-03-17 | — | — | US | claimed |
| US-7524485-B2 | Skin lightening agents, compositions and methods | UNILEVER HOME & PERSONAL CARE, USA, DIVISION OF CONOPCO, INC. (US) | 2009-04-28 | — | — | US | disclosed |
| US-6875425-B2 | Skin lightening agents, compositions and methods | UNILEVER HOME & PERSONAL CARE USA (US) | 2005-04-05 | — | — | US | disclosed |