Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 19/20 | 0.85 |
| ▸ | EGFR | P00533 | 1/20 | 0.64 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2913279 | 0.87 | CSF1R (0.64) | CSF1REGFR | |
| SCHEMBL4441524 | 0.85 | CSF1R (0.79) | CSF1R | |
| SCHEMBL27768805 | 0.84 | CSF1R (0.77) | CSF1R | |
| SCHEMBL4442692 | 0.83 | CSF1R (0.76) | CSF1REGFR | |
| SCHEMBL5929801 | 0.83 | CSF1R (1.00) | CSF1REGFR | |
| SCHEMBL2908163 | 0.83 | CSF1R (0.64) | CSF1REGFR | |
| SCHEMBL2909935 | 0.82 | CSF1R (0.85) | CSF1R | |
| SCHEMBL4072127 | 0.82 | CSF1R (0.71) | CSF1REGFR | |
| SCHEMBL2905491 | 0.82 | CSF1R (1.00) | CSF1R | |
| SCHEMBL2912117 | 0.81 | CSF1R (0.83) | CSF1REGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101611011-A | Compound | ASTRAZENECA AB (SE) | 2009-12-23 | — | — | CN | disclosed |
| US-20090270450-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2009-10-29 | — | — | US | disclosed |
| EP-2084134-A1 | CHEMICAL COMPOUNDS | AstraZeneca AB (SE) | 2009-08-05 | — | — | EP | disclosed |
| WO-2008056148-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2008-05-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270450-A1 | CHEMICAL COMPOUNDS | CSF1R, CSF3R, FLT3 | CSF1R 1/4885EGFR 415/4885ERBB2 266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.