Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 13/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3975487 | 1.00 | SIRT2 (0.44) | SIRT2PRKCAPRKCDPOLB | |
| SCHEMBL3420193 | 0.69 | — | — | |
| SCHEMBL4076179 | 0.67 | ALOX12 (0.31) | — | |
| SCHEMBL3975485 | 0.67 | ALOX12 (0.31) | — | |
| SCHEMBL25397359 | 0.64 | SIRT2 (0.39) | SIRT2 | |
| SCHEMBL8942878 | 0.64 | SIRT2 (0.36) | SIRT2PRKCA | |
| SCHEMBL8942837 | 0.64 | SIRT2 (0.36) | SIRT2PRKCA | |
| SCHEMBL7264368 | 0.64 | — | — | |
| SCHEMBL7262983 | 0.64 | — | — | |
| SCHEMBL7263919 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009052191-A1 | INTERNALLY MASKED NEOPENTYL SULFONYL ESTER CYCLIZATION RELEASE PRODRUGS OF ACAMPROSATE, COMPOSITIONS THEREOF, AND METHODS OF USE | XENOPORT, INC. (US) | 2009-04-23 | — | — | WO | disclosed |