Cyclohexylamine

Cyclohexylamine

SCHEMBL4076365

CCCCN(CCCC)C(=S)S.NC1CCCCC1

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
ALDH2 P05091 1/20 0.39
CA12 O43570 3/20 0.37
CA1 P00915 3/20 0.37
CA9 Q16790 3/20 0.37
CA2 P00918 2/20 0.37
ABCB11 O95342 1/20 0.36
CYP2E1 P05181 1/20 0.36
PTGS1 P23219 1/20 0.36
HTT P42858 1/20 0.36
GSDMD P57764 1/20 0.36
CYP1A2 P05177 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
NAAA Q02083 1/20 0.32
MGLL Q99685 1/20 0.32
ENPP2 Q13822 3/20 0.31
GNAI3 P08754 2/20 0.31
GNAO1 P09471 2/20 0.31
GNAI1 P63096 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2288683 0.82 ALDH1A1 (0.38) ALDH1A1ALDH2CA12CA1CA9
SCHEMBL1023076 0.82 MEN1 (0.41) ALDH1A1ALDH2CA12CA1CA9
Cyclohexylamine SCHEMBL635197 0.82 ALDH1A1 (0.38) ALDH1A1ALDH2CA12CA1CA9
SCHEMBL244470 0.80 ALDH1A1 (0.56) ALDH1A1ALDH2CA12CA1CA9
SCHEMBL28947901 0.80 ALDH1A1 (0.56) ALDH1A1ALDH2CA12CA1CA9
SCHEMBL23754635 0.78 ALDH1A1 (0.54) ALDH1A1ALDH2CA12CA1CA9
SCHEMBL2324997 0.78 ALDH1A1 (0.54) ALDH1A1ALDH2CA12CA1CA9
SCHEMBL20787858 0.78 ALDH1A1 (0.54) ALDH1A1ALDH2CA12CA1CA9
SCHEMBL11112773 0.78 ALDH1A1 (0.54) ALDH1A1ALDH2CA12CA1CA9
Hydrogen Sulfide SCHEMBL7977474 0.78 ALDH1A1 (0.54) ALDH1A1ALDH2CA12CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7081492-B1 Ambient temperature anhydrous liquid cross-linking agent ASPHALT PRODUCTS, LLC 2006-07-25 US claimed
EP-1842601-B1 Method for forming functional layers CIBA HOLDING INC (CH) 2009-07-22 EP disclosed
EP-1842601-A1 Method for forming functional layers Ciba Specialty Chemicals Holding Inc. (CH) 2007-10-10 EP disclosed
EP-1558402-B1 METHOD FOR PRODUCING UV ABSORPTION LAYERS ON SUBSTRATES CIBA SC HOLDING AG (CH) 2007-04-18 EP disclosed
US-7081492-B1 Ambient temperature anhydrous liquid cross-linking agent ASPHALT PRODUCTS, LLC 2006-07-25 US disclosed
EP-1576037-A1 METHOD FOR FORMING REACTIVE COATINGS Ciba SC Holding AG (CH) 2005-09-21 EP disclosed
EP-1572379-A2 METHOD FOR FORMING FUNCTIONAL LAYERS Ciba SC Holding AG (CH) 2005-09-14 EP disclosed
EP-1558402-A2 METHOD FOR PRODUCING UV ABSORPTION LAYERS ON SUBSTRATES Ciba Specialty Chemicals Holding Inc. (CH) 2005-08-03 EP disclosed
WO-2004056910-A1 METHOD FOR FORMING REACTIVE COATINGS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-07-08 WO disclosed
WO-2004056496-A2 METHOD FOR FORMING FUNCTIONAL LAYERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-07-08 WO disclosed
WO-2004035667-A2 METHOD FOR PRODUCING UV ABSORPTION LAYERS ON SUBSTRATES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-04-29 WO disclosed