Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.41 |
| ▸ | PPARA | Q07869 | 5/20 | 0.41 |
| ▸ | NPY4R | P50391 | 9/20 | 0.34 |
| ▸ | NPY1R | P25929 | 6/20 | 0.34 |
| ▸ | NPY2R | P49146 | 4/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4081916 | 0.84 | PPARG (0.44) | PPARGPPARANPY4RNPY1RNPY2R | |
| SCHEMBL4073286 | 0.83 | PPARG (0.44) | PPARGPPARANPY4RNPY1RNPY2R | |
| SCHEMBL4085908 | 0.82 | PPARG (0.44) | PPARGPPARANPY4RNPY1RNPY2R | |
| SCHEMBL4073437 | 0.80 | PPARA (0.53) | PPARGPPARAPPARD | |
| SCHEMBL4076714 | 0.78 | PPARG (0.40) | PPARGPPARANPY4RNPY1RNPY2R | |
| SCHEMBL4073315 | 0.77 | MTNR1A (0.38) | PPARGPPARANPY4RNPY1RNPY2R | |
| SCHEMBL5662321 | 0.75 | MTNR1A (0.37) | PPARGPPARANPY4RNPY1RNPY2R | |
| Arginine SCHEMBL4081910 | 0.74 | PPARG (0.51) | PPARGPPARAPPARD | |
| Arginine SCHEMBL4081908 | 0.74 | PPARG (0.51) | PPARGPPARAPPARD | |
| Arginine SCHEMBL4085902 | 0.73 | PPARA (0.51) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598293-B2 | Compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S LABORATORIES, INC. (US) | 2009-10-06 | — | — | US | claimed |