Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 3/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 12/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4106033 | 0.92 | CCR5 (0.40) | CCR5RORCKDM1ACASR | |
| SCHEMBL1096488 | 0.90 | CCR5 (0.39) | CCR5RORCKDM1ACASRESR1 | |
| SCHEMBL3573558 | 0.84 | DPP4 (0.40) | RORCCASRDPP4DPP7 | |
| SCHEMBL1105750 | 0.83 | CCR5 (0.40) | CCR5RORCESR1ESR2 | |
| SCHEMBL1095794 | 0.83 | CASR (0.45) | KDM1ACASR | |
| SCHEMBL4094906 | 0.82 | CCR5 (0.43) | CCR5RORCCASR | |
| SCHEMBL3576540 | 0.81 | CCR5 (0.39) | CCR5 | |
| SCHEMBL1097254 | 0.81 | ESR1 (0.39) | CCR5RORCKDM1ACASRESR1 | |
| SCHEMBL4114442 | 0.80 | CCR5 (0.41) | CCR5RORCCASR | |
| SCHEMBL1105717 | 0.80 | DPP4 (0.35) | RORCCASRESR1ESR2DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2085383-A1 | PIPERIDINE DERIVATIVES OR SALTS THEREOF | Astellas Pharma Inc. (JP) | 2009-08-05 | — | — | EP | disclosed |