Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL4076529 | 1.00 | — | — | |
| Bicarbonate SCHEMBL27897666 | 0.94 | — | — | |
| Bicarbonate SCHEMBL27900421 | 0.94 | — | — | |
| Bicarbonate SCHEMBL10746789 | 0.93 | CA1 (0.83) | — | |
| Bicarbonate SCHEMBL5458673 | 0.93 | CA1 (0.83) | — | |
| Bicarbonate SCHEMBL23213376 | 0.93 | CA1 (0.83) | — | |
| Bicarbonate SCHEMBL5458669 | 0.93 | — | — | |
| Bicarbonate SCHEMBL21405704 | 0.93 | — | — | |
| Bicarbonate SCHEMBL8531740 | 0.93 | CA1 (0.83) | — | |
| Bicarbonate SCHEMBL2718215 | 0.93 | CA1 (0.83) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110092890-B | Organic conjugated nano poly lattice and preparation method and application thereof | 南京邮电大学 | 2022-09-30 | — | — | CN | disclosed |
| CN-107955135-B | Conjugated organic lattice nano polymer and preparation and application methods thereof | 南京邮电大学 | 2020-02-14 | — | — | CN | disclosed |
| CN-110540761-A | Carbazole-phenothiazine organic dye and application thereof in dye-sensitized solar cell | UNIV NANJING POSTS & TELECOMMUNICATIONS | 2019-12-06 | — | — | CN | disclosed |
| CN-110092890-A | A kind of poly- lattice of organic conjugate nanometer and the preparation method and application thereof | 南京邮电大学 | 2019-08-06 | — | — | CN | disclosed |
| CN-110078738-A | A kind of A-D-A type nanometer unfilled corner grid and its preparation method and application with thermal activation delayed fluorescence property | 南京邮电大学 | 2019-08-02 | — | — | CN | disclosed |
| CN-105482813-B | Novel Fluorene class bipolarity fluorescent material based on anthraquinone radicals and its application in Organic Light Emitting Diode | 南京邮电大学 | 2018-05-18 | — | — | CN | disclosed |
| CN-107955135-A | It is conjugated organic grid nanometer polymer and its methods for making and using same | 南京邮电大学 | 2018-04-24 | — | — | CN | disclosed |
| CN-102421454-A | Pet radiotracers for imaging fatty acid metablolism and storage | UNIV WASHINGTON | 2012-04-18 | — | — | CN | disclosed |
| CN-101123995-B | Stilbene derivatives and their use for binding and imaging amyloid plaques | UNIV PENNSYLVANIA | 2011-11-16 | — | — | CN | disclosed |
| CN-101484190-B | Radiolabeled dihydrotetrabenazine derivatives and their use as imaging agents | UNIV PENNSYLVANIA | 2011-07-20 | — | — | CN | disclosed |
| CN-101123995-A | Stilbene derivatives and their use for binding and imaging amyloid plaques | UNIV PENNSYLVANIA (US) | 2008-02-13 | — | — | CN | disclosed |
| WO-2007130365-A2 | RADIOLABELED DIHYDROTETRABENAZINE DERIVATIVES AND THEIR USE AS IMAGING AGENTS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2007-11-15 | — | — | WO | disclosed |
| EP-1841465-A2 | STILBENE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES | The Trustees of The University of Pennsylvania (US) | 2007-10-10 | — | — | EP | disclosed |
| EP-1838298-A2 | STILBENE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES | The Trustees of The University of Pennsylvania (US) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006078384-A2 | STILBENE DERIVATIVES AND THEIR USE | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2006-07-27 | — | — | WO | disclosed |
| WO-2006066104-A2 | STILBENE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2006-06-22 | — | — | WO | disclosed |
| US-5137988-A | Reacting a halo-nitro aromatic compound with a dihydroxy-terminated oligomer; reduction | AMOCO CORPORATION (US) | 1992-08-11 | — | — | US | disclosed |
| US-4959424-A | AMINATION, DEHALOGENATION, COPPER CATALYST | AMOCO CORPORATION (US) | 1990-09-25 | — | — | US | disclosed |
| US-4748227-A | Process for preparing poly(aryl ether)ketones using a sodium carbonate/organic acid salt catalyst | AMOCO CORPORATION (US) | 1988-05-31 | — | — | US | disclosed |
| EP-0254585-A2 | Amino terminated poly(aryl ether ketones) | AMOCO CORPORATION (US) | 1988-01-27 | — | — | EP | disclosed |