Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4249654 | 0.83 | TSHR (0.55) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL30376807 | 0.80 | TSHR (0.50) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL27821520 | 0.78 | TSHR (0.61) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL34872 | 0.78 | TSHR (0.61) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL28785943 | 0.78 | TSHR (0.61) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL27779858 | 0.78 | TSHR (0.38) | TSHRHPGDALDH1A1 | |
| SCHEMBL241400 | 0.78 | TSHR (0.39) | TSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL95157 | 0.78 | TSHR (0.64) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL12570110 | 0.77 | TSHR (0.55) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL109189 | 0.77 | TSHR (0.47) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8664350-B2 | Polymeric coupling agents | LUBRIZOL LIMITED (GB) | 2014-03-04 | — | — | US | disclosed |
| EP-2084219-B1 | POLYMERIC COUPLING AGENTS | LUBRIZOL LTD (GB) | 2012-09-05 | — | — | EP | disclosed |
| US-20090306252-A1 | Polymeric Coupling Agents | LUBRIZOL LIMITED (GB) | 2009-12-10 | — | — | US | disclosed |
| EP-2084219-A1 | POLYMERIC COUPLING AGENTS | Lubrizol Limited (GB) | 2009-08-05 | — | — | EP | disclosed |
| WO-2008049840-A1 | POLYMERIC COUPLING AGENTS | LUBRIZOL LIMITED (GB) | 2008-05-02 | — | — | WO | disclosed |