Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 20/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2887172 | 0.88 | EGLN1 (0.60) | EGLN1 | |
| SCHEMBL2880575 | 0.80 | LMNA (0.45) | EGLN1 | |
| SCHEMBL3979065 | 0.77 | EGLN1 (0.41) | EGLN1 | |
| SCHEMBL2889304 | 0.69 | EGLN1 (0.62) | EGLN1 | |
| SCHEMBL2888053 | 0.66 | LMNA (0.47) | EGLN1 | |
| SCHEMBL12503281 | 0.65 | EGLN1 (0.77) | EGLN1 | |
| SCHEMBL12503277 | 0.65 | EGLN1 (0.77) | EGLN1 | |
| SCHEMBL14150645 | 0.64 | EGLN1 (0.65) | EGLN1 | |
| SCHEMBL14150387 | 0.64 | EGLN1 (0.65) | EGLN1 | |
| SCHEMBL14150552 | 0.64 | EGLN1 (0.65) | EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2016078-A2 | PYRROLO- AND THIAZOLO-PYRIDINE COMPOUNDS AS HIF MODULATORS | FIBROGEN, INC. (US) | 2009-01-21 | — | — | EP | disclosed |
| WO-2007115315-A2 | PYRROLO- AND THIAZOLO-PYRIDINE COMPOUNDS AS HIF MODULATORS | FIBROGEN, INC. (US) | 2007-10-11 | — | — | WO | disclosed |