Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 4/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.39 |
| ▸ | ACACB | O00763 | 3/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4085297 | 0.90 | PDE4A (0.37) | PDE4APDE4BPDE4CPDE4DACACB | |
| SCHEMBL3974826 | 0.74 | PTGDR2 (0.42) | ACACBITGB1ITGA4P2RX3MAOB | |
| SCHEMBL3969315 | 0.71 | P2RX3 (0.36) | P2RX3KDM4E | |
| SCHEMBL31527998 | 0.65 | MEN1 (0.57) | KDM4ELMNAMAOB | |
| SCHEMBL11640849 | 0.60 | PARP15 (0.53) | KDM4ELMNA | |
| SCHEMBL11442713 | 0.60 | GAA (0.58) | KDM4ELMNAGAA | |
| SCHEMBL18906057 | 0.60 | SRD5A2 (0.57) | KDM4ELMNAGAA | |
| SCHEMBL7114833 | 0.60 | MRGPRX4 (0.53) | MAOB | |
| Hydrochloric Acid SCHEMBL7526696 | 0.59 | MRGPRX4 (0.52) | MAOB | |
| SCHEMBL28270607 | 0.59 | KMT2A (0.52) | KDM4ELMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009044147-A1 | INDOLIZINE DERIVATIVES WITH CRTH2 RECEPTOR AFFINITY FOR THE TREATMENT OF INFLAMMATORY DISEASES | ARGENTA DISCOVERY LIMITED (GB) | 2009-04-09 | — | — | WO | disclosed |