Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | HRH1 | P35367 | 1/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | GALR3 | O60755 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14611305 | 1.00 | SMN1; SMN2 (0.59) | SMN1; SMN2MEN1KMT2ALMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL10720917 | 0.98 | SMN1; SMN2 (0.62) | SMN1; SMN2MEN1KMT2ALMNACYP1A2 | |
| SCHEMBL22188617 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2MEN1KMT2ALMNACYP1A2 | |
| SCHEMBL20680945 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2MEN1KMT2ALMNACYP1A2 | |
| SCHEMBL14236467 | 0.83 | SMN1; SMN2 (0.42) | SMN1; SMN2MEN1KMT2ALMNACYP1A2 | |
| SCHEMBL14236225 | 0.83 | SMN1; SMN2 (0.42) | SMN1; SMN2MEN1KMT2ALMNACYP1A2 | |
| Triacetin SCHEMBL3870 | 0.83 | TDP1 (0.56) | SMN1; SMN2MEN1KMT2ALMNACYP1A2 | |
| Triacetin SCHEMBL821340 | 0.83 | TDP1 (0.56) | SMN1; SMN2MEN1KMT2ALMNACYP1A2 | |
| SCHEMBL30925322 | 0.81 | SMN1; SMN2 (0.56) | SMN1; SMN2MEN1KMT2ALMNACYP1A2 | |
| SCHEMBL10868982 | 0.81 | TDP1 (0.43) | SMN1; SMN2MEN1KMT2ALMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7507859-B2 | Functional synthetic molecules and macromolecules for gene delivery | FIFTH BASE LLC (US) | 2009-03-24 | — | — | US | disclosed |
| US-7507859-B2 | Functional synthetic molecules and macromolecules for gene delivery | FIFTH BASE LLC (US) | 2009-03-24 | — | — | US | disclosed |
| EP-1644479-A4 | FUNCTIONAL SYNTHETIC MOLECULES AND MACROMOLECULES FOR GENE DELIVERY | GRINSTAFF MARK W (US) | 2008-04-23 | — | — | EP | disclosed |
| US-20060241071-A1 | Functional synthetic molecules and macromolecules for gene delivery | FIFTH BASE LLC | 2006-10-26 | — | — | US | disclosed |
| EP-1644479-A2 | FUNCTIONAL SYNTHETIC MOLECULES AND MACROMOLECULES FOR GENE DELIVERY | Grinstaff, Mark, W. (US) | 2006-04-12 | — | — | EP | disclosed |
| WO-2005007810-A2 | FUNCTIONAL SYNTHETIC MOLECULES AND MACROMOLECULES FOR GENE DELIVERY | GRINSTAFF MARK W (US) | 2005-01-27 | — | — | WO | disclosed |
| EP-0187298-B1 | ORGANIC QUATERNARY AMMONIUM COMPOUNDS AND PROCESS FOR THEIR PREPARATION | INTEROX Société Anonyme (BE) | 1990-05-23 | — | — | EP | disclosed |
| EP-0187298-A2 | Organic quaternary ammonium compounds and process for their preparation | INTEROX Société Anonyme (BE) | 1986-07-16 | — | — | EP | disclosed |
| EP-0186052-A1 | Process for activating hydrogen peroxide in washing and disinfecting baths | INTEROX Société Anonyme (BE) | 1986-07-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241071-A1 | Functional synthetic molecules and macromolecules for gene delivery | ANXA6, STING1, POLRMT | SMN1; SMN2 3525/4885MEN1 3002/4885KMT2A 1652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.