Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.56 |
| ▸ | CNR1 | P21554 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1464717 | 0.90 | CNR2 (0.67) | CNR2CNR1RAB9ANPC1MAPK14 | |
| SCHEMBL1464450 | 0.87 | CNR2 (0.62) | CNR2CNR1RAB9ANPC1MAPK14 | |
| SCHEMBL4077579 | 0.85 | CNR2 (0.64) | CNR2CNR1RAB9ANPC1MAPK14 | |
| SCHEMBL766938 | 0.81 | CNR2 (0.79) | CNR2CNR1RAB9ANPC1MAPK14 | |
| SCHEMBL1465839 | 0.79 | CNR2 (0.65) | CNR2CNR1RAB9ANPC1MAPK14 | |
| SCHEMBL1465063 | 0.78 | CNR2 (0.67) | CNR2CNR1RAB9ANPC1MAPK14 | |
| SCHEMBL1464880 | 0.78 | CNR2 (0.61) | CNR2CNR1RAB9ANPC1MAPK14 | |
| SCHEMBL1464681 | 0.77 | CNR2 (0.79) | CNR2CNR1RAB9ANPC1MAPK14 | |
| SCHEMBL1464517 | 0.77 | CNR2 (0.69) | CNR2CNR1RAB9ANPC1MAPK14 | |
| SCHEMBL1463932 | 0.77 | CNR2 (0.72) | CNR2CNR1RAB9ANPC1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | claimed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | claimed |
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | disclosed |