Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.64 |
| ▸ | CNR1 | P21554 | 3/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RET | P07949 | 3/20 | 0.42 |
| ▸ | CSF1R | P07333 | 2/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CCDC6 | Q16204 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1464717 | 0.95 | CNR2 (0.67) | CNR2CNR1GAAEGFRRAB9A | |
| SCHEMBL1464503 | 0.89 | CNR2 (0.80) | CNR2CNR1GAARETCSF1R | |
| SCHEMBL4076909 | 0.85 | CNR2 (0.56) | CNR2CNR1GAAEGFRRAB9A | |
| SCHEMBL1463539 | 0.80 | CNR2 (0.80) | CNR2CNR1GAAEGFRRAB9A | |
| SCHEMBL1464776 | 0.80 | CNR2 (0.84) | CNR2CNR1GAAEGFRRAB9A | |
| SCHEMBL1465703 | 0.80 | CNR2 (0.80) | CNR2CNR1GAACSF1REGFR | |
| SCHEMBL469406 | 0.79 | CNR2 (1.00) | CNR2CNR1GAAEGFRRAB9A | |
| SCHEMBL1464383 | 0.79 | CNR2 (0.78) | CNR2CNR1GAAEGFRRAB9A | |
| SCHEMBL766938 | 0.79 | CNR2 (0.79) | CNR2CNR1GAAEGFRRAB9A | |
| SCHEMBL1465761 | 0.79 | CNR2 (0.78) | CNR2CNR1GAAEGFRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | disclosed |