Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 3/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4075308 | 0.87 | MEN1 (0.50) | MEN1KMT2AMAPTTDP1GAA | |
| SCHEMBL4087581 | 0.86 | AR (0.52) | MEN1KMT2AMAPTTDP1GAA | |
| SCHEMBL4077609 | 0.85 | MAPT (0.52) | MEN1KMT2AMAPTTDP1GAA | |
| SCHEMBL4075018 | 0.85 | SMN1; SMN2 (0.51) | MEN1KMT2AMAPTARNPC1 | |
| SCHEMBL4076674 | 0.85 | MAPT (0.52) | MEN1KMT2AMAPTTDP1GAA | |
| SCHEMBL3977547 | 0.85 | MEN1 (0.48) | MEN1KMT2AMAPTTDP1GAA | |
| SCHEMBL4078988 | 0.84 | GAA (0.55) | MEN1KMT2AMAPTTDP1GAA | |
| SCHEMBL4078198 | 0.83 | AR (0.54) | MEN1KMT2AMAPTGAAAR | |
| SCHEMBL4076268 | 0.82 | SMN1; SMN2 (0.51) | MEN1KMT2AMAPTTDP1GAA | |
| SCHEMBL4484758 | 0.82 | SIRT5 (0.42) | MEN1KMT2AMAPTTDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054410-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | Wyeth (US) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008021331-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | WYETH (US) | 2008-02-21 | — | — | WO | disclosed |