Ethylene Glycol

Ethylene Glycol

SCHEMBL4077820

O=C(O)CCCC1(C(=O)O)CCCCCC1.OCCO

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.52
TBXAS1 P24557 2/20 0.42
CAMK2A Q9UQM7 1/20 0.41
CYP4F2 P78329 4/20 0.41
CYP4A11 Q02928 4/20 0.41
GPR84 Q9NQS5 1/20 0.39
FFAR1 O14842 1/20 0.39
FFAR4 Q5NUL3 1/20 0.39
CYP1A2 P05177 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
MAPK1 P28482 1/20 0.36
LMNA P02545 3/20 0.36
SLC22A6 Q4U2R8 1/20 0.36
TSHR P16473 2/20 0.34
NFKB1 P19838 1/20 0.34
PMP22 Q01453 1/20 0.34
MME P08473 1/20 0.33
USP2 O75604 1/20 0.32
ALDH1A1 P00352 1/20 0.32
BLM P54132 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL2877904 1.00 CYP2C19 (0.52) CYP2C19TBXAS1CAMK2ACYP4F2CYP4A11
Ethylene Glycol SCHEMBL16857993 1.00 CYP2C19 (0.52) CYP2C19TBXAS1CAMK2ACYP4F2CYP4A11
Ethylene Glycol SCHEMBL250392 0.98 CYP2C19 (0.48) CYP2C19TBXAS1CAMK2ACYP4F2CYP4A11
SCHEMBL220603 0.94 CYP2C19 (0.57) CYP2C19TBXAS1CAMK2ACYP4F2CYP4A11
SCHEMBL3101468 0.94 CYP2C19 (0.57) CYP2C19TBXAS1CAMK2ACYP4F2CYP4A11
SCHEMBL249733 0.94 CYP2C19 (0.57) CYP2C19TBXAS1CAMK2ACYP4F2CYP4A11
SCHEMBL249881 0.94 CYP2C19 (0.57) CYP2C19TBXAS1CAMK2ACYP4F2CYP4A11
SCHEMBL248718 0.94 CYP2C19 (0.57) CYP2C19TBXAS1CAMK2ACYP4F2CYP4A11
SCHEMBL250972 0.94 CYP2C19 (0.57) CYP2C19TBXAS1CAMK2ACYP4F2CYP4A11
Cyclohexane SCHEMBL8602472 0.94 CYP2C19 (0.57) CYP2C19TBXAS1CAMK2ACYP4F2CYP4A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7282253-B2 Mixture of a polyurethane matrix binder with soft segments and rigid segments; the soft segments of heptamethyleneglycol, pentamethyleneglycol or hexamethyleneglycol polycarbonates and a hexamethylene adipic acid polyester, the rigid segments of polyurethane ALCANTARA S.P.A. (IT) 2007-10-16 US claimed
US-7144535-B2 Procedure for the preparation of a highly durable composite textile material workable at high temperature, and the composite textile material thus obtained ALCANTARA S.P.A. (IT) 2006-12-05 US claimed
US-20030151154-A1 Procedure for the preparation of a highly durable composite textile material workable at high temperature, and the composite textile material thus obtained ALCANTARA S.P.A. (IT) 2003-08-14 US claimed
EP-1323859-A2 Procedure for the preparation of a highly durable composite textile material workable at high temperature, and the composite textile material thus obtained ALCANTARA S.p.A. (IT) 2003-07-02 EP claimed
EP-1353006-B1 Process for the production of micro-fibrous suede non-woven fabric ALCANTARA SPA (IT) 2009-07-22 EP disclosed
EP-1323859-B1 Procedure for the preparation of a highly durable composite textile material workable at high temperature ALCANTARA SPA (IT) 2008-10-22 EP disclosed
US-7144535-B2 Procedure for the preparation of a highly durable composite textile material workable at high temperature, and the composite textile material thus obtained ALCANTARA S.P.A. (IT) 2006-12-05 US disclosed
US-6890602-B2 Process for the production of micro-fibrous suede non-woven fabric ALCANTARA S.P.A. (IT) 2005-05-10 US disclosed
US-20040006857-A1 Process for the production of micro-fibrous suede non-woven fabric ALCANTARA S.P.A. (IT) 2004-01-15 US disclosed
US-20030225240-A1 Modified urethane compositions containing adducts of O-phthalic anhydride ester polyols UNIROYAL CHEMICAL COMPANY, INC. 2003-12-04 US disclosed
EP-1353006-A1 Process for the production of micro-fibrous suede non-woven fabric ALCANTARA S.p.A. (IT) 2003-10-15 EP disclosed
US-20030151154-A1 Procedure for the preparation of a highly durable composite textile material workable at high temperature, and the composite textile material thus obtained ALCANTARA S.P.A. (IT) 2003-08-14 US disclosed
EP-1323859-A2 Procedure for the preparation of a highly durable composite textile material workable at high temperature, and the composite textile material thus obtained ALCANTARA S.p.A. (IT) 2003-07-02 EP disclosed
WO-2002004536-A2 MODIFIED URETHANE COMPOSITIONS CONTAINING ADDUCTS OF O-PHTHALIC ANHYDRIDE ESTER POLYOLS UNIROYAL CHEMICAL COMPANY, INC. (US) 2002-01-17 WO disclosed
US-5308697-A Sheath-core polyesterurethane KANEBO, LTD. (JP) 1994-05-03 US disclosed
EP-0548364-A1 POTENTIALLY ELASTIC CONJUGATE FIBER, PRODUCTION THEREOF, AND PRODUCTION OF FIBROUS STRUCTURE WITH ELASTICITY IN EXPANSION AND CONTRACTION KANEBO LTD. (JP) 1993-06-30 EP disclosed
US-4515852-A ACXRYL-MODIFIED POLYURETHANE SPREAD ON POLYURETHANE ELASTOMER SURFACE KURARAY CO., LTD. (JP) 1985-05-07 US disclosed
US-4415693-A Stabilization of polyesteramides with urethanes THE UPJOHN COMPANY (US) 1983-11-15 US disclosed
EP-0062995-A1 Sulfur curable millable polyurethane gum UNIROYAL, INC. (US) 1982-10-20 EP disclosed
US-4335231-A CONTAINING AN UNSATURATED GLYCOL COMPONENT UNIROYAL, INC. (US) 1982-06-15 US disclosed