Ethylene Glycol

Ethylene Glycol

SCHEMBL250392

O=C(O)CCCC1(C(=O)O)CCCC1.OCCO

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.48
CAMK2A Q9UQM7 1/20 0.43
CYP4F2 P78329 5/20 0.42
CYP4A11 Q02928 5/20 0.42
TBXAS1 P24557 2/20 0.40
GPR84 Q9NQS5 1/20 0.40
FFAR1 O14842 1/20 0.40
FFAR4 Q5NUL3 1/20 0.40
LMNA P02545 2/20 0.37
SLC22A6 Q4U2R8 1/20 0.37
TSHR P16473 1/20 0.36
NFKB1 P19838 1/20 0.36
PMP22 Q01453 1/20 0.36
MME P08473 1/20 0.33
CYP1A2 P05177 1/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
BBOX1 O75936 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL16857993 0.98 CYP2C19 (0.52) CYP2C19CAMK2ACYP4F2CYP4A11TBXAS1
Ethylene Glycol SCHEMBL4077820 0.98 CYP2C19 (0.52) CYP2C19CAMK2ACYP4F2CYP4A11TBXAS1
Ethylene Glycol SCHEMBL2877904 0.98 CYP2C19 (0.52) CYP2C19CAMK2ACYP4F2CYP4A11TBXAS1
SCHEMBL220706 0.94 CYP2C19 (0.54) CYP2C19CAMK2ACYP4F2CYP4A11TBXAS1
Ethylene Glycol SCHEMBL9623667 0.93 CYP4F2 (0.47) CYP2C19CAMK2ACYP4F2CYP4A11TBXAS1
SCHEMBL220603 0.92 CYP2C19 (0.57) CYP2C19CAMK2ACYP4F2CYP4A11TBXAS1
SCHEMBL3101468 0.92 CYP2C19 (0.57) CYP2C19CAMK2ACYP4F2CYP4A11TBXAS1
SCHEMBL249733 0.92 CYP2C19 (0.57) CYP2C19CAMK2ACYP4F2CYP4A11TBXAS1
SCHEMBL248718 0.92 CYP2C19 (0.57) CYP2C19CAMK2ACYP4F2CYP4A11TBXAS1
Ethylene Glycol SCHEMBL6051015 0.92 CAMK2A (0.52) CYP2C19CAMK2ACYP4F2CYP4A11TBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109337035-A High resistance to toluene polyurethane resin for superfine fiber synthetic leather and preparation method thereof 江苏华峰超纤材料有限公司 2019-02-15 CN claimed
EP-3400249-A2 CURABLE POLYFARNESENE-BASED COMPOSITIONS Fina Technology, Inc. (US) 2018-11-14 EP claimed
WO-2017065864-A2 CURABLE POLYFARNESENE-BASED COMPOSITIONS FINA TECHNOLOGY, INC. (US) 2017-04-20 WO claimed
US-8088838-B2 Cone material in endodontic treatment NATIONAL TAIWAN UNIVERSITY (TW) 2012-01-03 US claimed
US-20090156710-A1 Cone Material in Endodontic Treatment NATIONAL TAIWAN UNIVERSITY (TW) 2009-06-18 US claimed
US-7144535-B2 Procedure for the preparation of a highly durable composite textile material workable at high temperature, and the composite textile material thus obtained ALCANTARA S.P.A. (IT) 2006-12-05 US claimed
EP-0934350-B1 BRANCHED POLYESTERS COGNIS CORP (US) 2004-08-18 EP claimed
EP-0928301-B1 FLUID COMPOSITION FOR PHYSIOLOGICAL SEPARATIONS COGNIS CORP (US) 2004-01-07 EP claimed
US-20030151154-A1 Procedure for the preparation of a highly durable composite textile material workable at high temperature, and the composite textile material thus obtained ALCANTARA S.P.A. (IT) 2003-08-14 US claimed
EP-1323859-A2 Procedure for the preparation of a highly durable composite textile material workable at high temperature, and the composite textile material thus obtained ALCANTARA S.p.A. (IT) 2003-07-02 EP claimed
US-5589543-A CHAIN EXTENTION OF POLYETHERURETHANE COPOLYMER TELECHELIC POLYMERS AMOCO CORPORATION (US) 1996-12-31 US claimed
EP-0089181-B1 POWDER COATING PROCESS FOR FORMING SOFT FLEXIBLE POLYURETHANE FILM Deseret Medical, Inc. (US) 1987-07-15 EP claimed
EP-0089180-B1 CRYSTALLINE, GRINDABLE POLYURETHANE PREPOLYMERS WARNER-LAMBERT COMPANY (US) 1986-06-11 EP claimed
US-4325759-A Preparation of TNT-thermoplastic polymer granules readily soluble in a TNT melt THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1982-04-20 US claimed
US-4284442-A EXPLOSIVES THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1981-08-18 US claimed
US-20230265235-A1 CURABLE POLYFARNESENE-BASED COMPOSITIONS FINA TECHNOLOGY, INC. (US) 2023-08-24 US disclosed
US-11634531-B2 Curable polyfarnesene-based compositions FINA TECHNOLOGY, INC. (US) 2023-04-25 US disclosed
US-4284442-A EXPLOSIVES THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1981-08-18 US disclosed
US-4016120-A BLOCKED ISOCYANATE GROUPS; REACTING A URETHANE PREPOLYMER WITH A POLYALKYLENE POLYAMINE KAO SOAP CO., LTD. (JA) 1977-04-05 US disclosed
US-4016121-A BLOCKED ISOCYANATE GROUPS; REACTING A URETHANE PREPOLYMER WITH A POLYALKYLENE POLYAMINE KAO SOAP CO., LTD. (JA) 1977-04-05 US disclosed