⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9397432 | 1.00 | — | — | |
| SCHEMBL6236877 | 0.95 | THRB (0.39) | — | |
| SCHEMBL9667909 | 0.95 | THRB (0.39) | — | |
| SCHEMBL28483386 | 0.95 | THRB (0.39) | — | |
| SCHEMBL28552565 | 0.95 | THRB (0.39) | — | |
| SCHEMBL24163589 | 0.77 | — | — | |
| SCHEMBL5930483 | 0.77 | — | — | |
| SCHEMBL18530027 | 0.77 | — | — | |
| SCHEMBL18530024 | 0.77 | — | — | |
| SCHEMBL22436892 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103958049-A | Production of 18f- labelled compounds comprising hydrolytic deprotection step and solid phase extraction | GE HEALTHCARE LTD | 2014-07-30 | — | — | CN | claimed |
| EP-3129039-A1 | A COMPOSITION COMPRISING ASTRAGALUS MEMBRANACEUS EXTRACT FOR PREVENTING/TREATING BRAIN INJURY AND ITS PREPARATION METHOD | Phytohealth Corporation (CN) | 2017-02-15 | — | — | EP | disclosed |
| WO-2015154691-A1 | A COMPOSITION COMPRISING ASTRAGALUS MEMBRANACEUS EXTRACT FOR PREVENTING/TREATING BRAIN INJURY AND ITS PREPARATION METHOD | PHYTOHEALTH CORPORATION (CN) | 2015-10-15 | — | — | WO | disclosed |
| CN-103958049-A | Production of 18f- labelled compounds comprising hydrolytic deprotection step and solid phase extraction | GE HEALTHCARE LTD | 2014-07-30 | — | — | CN | disclosed |
| CN-102740868-A | Recombinant beta-glucosidase variants for production of soluble sugars from cellulosic biomass | CODEXIS INC | 2012-10-17 | — | — | CN | disclosed |
| EP-2134850-A1 | GENERATION OF CHEMICAL BUILDING BLOCKS FROM PLANT BIOMASS BY SELECTIVE DEPOLYMERIZATION | Sued-Chemie AG (DE) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008113585-A1 | GENERATION OF CHEMICAL BUILDING BLOCKS FROM PLANT BIOMASS BY SELECTIVE DEPOLYMERIZATION | Süd-Chemie AG (DE) | 2008-09-25 | — | — | WO | disclosed |