Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.68 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29038977 | 0.90 | CYP19A1 (0.63) | CYP19A1CYP2A6CA2ALDH1A1CA12 | |
| SCHEMBL1343704 | 0.90 | CYP19A1 (0.63) | CYP19A1CYP2A6CA2ALDH1A1CA12 | |
| SCHEMBL22044381 | 0.88 | CYP19A1 (0.57) | CYP19A1CYP2A6CA2ALDH1A1CA12 | |
| SCHEMBL29038984 | 0.84 | CYP19A1 (0.53) | CYP19A1CA2CA12CA9TSHR | |
| SCHEMBL13403830 | 0.82 | CYP19A1 (0.52) | CYP19A1CYP2A6CA2ALDH1A1CA12 | |
| SCHEMBL2355389 | 0.82 | CYP19A1 (1.00) | CYP19A1CYP2A6CA2ALDH1A1CA12 | |
| SCHEMBL45942 | 0.80 | CA2 (0.69) | CYP2A6CA2ALDH1A1CA12CA3 | |
| Water SCHEMBL28254092 | 0.80 | CA2 (0.69) | CYP2A6CA2ALDH1A1CA12CA3 | |
| Water SCHEMBL28189314 | 0.80 | CA2 (0.69) | CYP2A6CA2ALDH1A1CA12CA3 | |
| SCHEMBL2503454 | 0.80 | CA2 (0.69) | CYP2A6CA2ALDH1A1CA12CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116375657-A | Preparation method of letrozole impurity A | 南京亿华药业有限公司 | 2023-07-04 | — | — | CN | claimed |
| CN-120092029-A | Resin composition, cured product, prepreg, metal foil-clad laminate, resin composite sheet, and printed wiring board | 三菱瓦斯化学株式会社 | 2025-06-03 | — | — | CN | disclosed |
| CN-114787120-B | Compound and method for producing same, resin composition, resin sheet, multilayer printed wiring board, and semiconductor device | 三菱瓦斯化学株式会社 | 2024-08-09 | — | — | CN | disclosed |
| CN-118251445-A | Cyclic organosiloxane containing imide bond and polymerizable unsaturated bond and curable resin composition containing the same | 信越化学工业株式会社 | 2024-06-25 | — | — | CN | disclosed |
| CN-116813824-A | Resin composition, resin sheet, multilayer printed wiring board, and semiconductor device | 三菱瓦斯化学株式会社 | 2023-09-29 | — | — | CN | disclosed |
| CN-116490350-A | Resin composition, prepreg, resin sheet, metal foil-clad laminate, and printed wiring board | 三菱瓦斯化学株式会社 | 2023-07-25 | — | — | CN | disclosed |
| CN-116375657-A | Preparation method of letrozole impurity A | 南京亿华药业有限公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-116375657-A | Preparation method of letrozole impurity A | 南京亿华药业有限公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-116375657-A | Preparation method of letrozole impurity A | 南京亿华药业有限公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-113348079-B | Resin composition, resin sheet, multilayer printed wiring board, and semiconductor device | 三菱瓦斯化学株式会社 | 2023-06-02 | — | — | CN | disclosed |
| WO-2007039912-A1 | A ONE POT PROCESS FOR THE PREPARATION OF 4-[1-CYANOPHENYL)-1-(1,2,4-TRIAZOL-1-YL)METHYL]BENZONITRILE | USV LIMITED (IN) | 2007-04-12 | — | — | WO | disclosed |
| US-20070066831-A1 | Process for the preparation of letrozole | SICOR, INC. | 2007-03-22 | — | — | US | disclosed |
| US-20060128775-A1 | Regiospecific process for the preparation of 4-[1- (4-cyanophenyl)-1-(1,2,4-triazol-1-yl) methyl] benzonitrile | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2006-06-15 | — | — | US | disclosed |
| EP-1594850-A2 | REGIOSPECIFIC PROCESS FOR THE PREPARATION OF 4- 1- (4-CYANOPHENYL)-1-(1,2,4-TRIAZOL-1-YL)METHYL]BENZONITRILE | Sun Pharmaceuticals Industries Ltd. (IN) | 2005-11-16 | — | — | EP | disclosed |
| US-6914108-B2 | Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-07-05 | — | — | US | disclosed |
| WO-2004076409-A2 | REGIOSPECIFIC PROCESS FOR THE PREPARATION OF 4-[1- (4-CYANOPHENYL)-1-(1,2,4-TRIAZOL-1-YL)METHYL]BENZONITRILE | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2004-09-10 | — | — | WO | disclosed |
| US-20030203810-A1 | Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED | 2003-10-30 | — | — | US | disclosed |
| US-6586356-B2 | Coordination catalyst | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-07-01 | — | — | US | disclosed |
| US-20010020075-A1 | Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-09-06 | — | — | US | disclosed |
| EP-1113026-A2 | Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-07-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066831-A1 | Process for the preparation of letrozole | CYP19A1, CYP4B1, CYP3A4 | CYP19A1 1/4885CYP2A6 163/4885CA2 1657/4885 |
| US-20060128775-A1 | Regiospecific process for the preparation of 4-[1- (4-cyanophenyl)-1-(1,2,4-triazol-1-yl) methyl] benzonitrile | CYP4B1, KDM4B, CYP3A4 | CYP19A1 1741/4885CYP2A6 1022/4885CA2 2994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.