⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19940652 | 0.96 | PHGDH (0.42) | — | |
| SCHEMBL9009900 | 0.96 | — | — | |
| SCHEMBL14733936 | 0.84 | — | — | |
| SCHEMBL15234029 | 0.81 | ADH1A (0.32) | — | |
| SCHEMBL2140852 | 0.77 | ADH1A (0.38) | — | |
| SCHEMBL1170432 | 0.74 | PHGDH (0.42) | — | |
| SCHEMBL9930440 | 0.72 | ADH1A (0.35) | — | |
| SCHEMBL14960417 | 0.72 | — | — | |
| SCHEMBL3585841 | 0.69 | — | — | |
| SCHEMBL8011374 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1175420-B1 | PROCESS FOR PREPARING N6-SUBSTITUTED DEAZA-ADENOSINE DERIVATIVES | AVENTIS PHARMA INC (US) | 2003-03-26 | — | — | EP | claimed |
| EP-1175420-A2 | PROCESS FOR PREPARING N6-SUBSTITUTED DEAZA-ADENOSINE DERIVATIVES | Aventis Pharmaceuticals Products Inc. (US) | 2002-01-30 | — | — | EP | claimed |
| US-6184382-B1 | 4-(7-((1-((3-CHLOROTHIEN-2-YL)METHYL)PROPYL)AMINO)-3H-IMIDAZO (4, 5-B)PYRID-3-YL) N-ETHYL-2,3-DIHYDROXYCYCLOPENTANECARBOXAMIDE ARE USEFUL AS CARDIOVASCULAR AGENTS, ANTIHYPERTENSIVE, ANTI-ISCHEMIC AGENTS, | AVENTIS PHARMACEUTICALS PRODUCTS INC. | 2001-02-06 | — | — | US | claimed |
| WO-2000037469-A2 | PROCESS FOR PREPARING N6-SUBSTITUTED DEAZA-ADENOSINE DERIVATIVES | AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) | 2000-06-29 | — | — | WO | claimed |
| US-7598252-B2 | Compounds specific to adenosine A, receptors and uses thereof | OSI PHARMACEUTICALS, INC. (US) | 2009-10-06 | — | — | US | disclosed |
| US-20090082369-A1 | Pyrrolo[2,3d]pyrimidine compositions and their use | OSI PHARMACEUTICALS, INC. | 2009-03-26 | — | — | US | disclosed |
| EP-2011499-A2 | Pyrrolo[2,3d]Pyrimidine compositions and their use | OSI Pharmaceuticals, Inc. (US) | 2009-01-07 | — | — | EP | disclosed |
| US-7429574-B2 | 4-heterocyclo-pyrrolo[2,3d] pyrimidine compositions and their use | OSI PHARMACEUTICALS, INC. (US) | 2008-09-30 | — | — | US | disclosed |
| US-7417153-B2 | Method for the production of 3-amino-5-(hydroxymethyl)cyclopentane-1,2-diol derivatives | LONZA AG (CH) | 2008-08-26 | — | — | US | disclosed |
| US-20080070936-A1 | Compounds specific to adenosine A1 receptors and uses thereof | OSI PHARMACEUTICALS, INC. | 2008-03-20 | — | — | US | disclosed |
| EP-1771434-A2 | METHOD FOR THE PRODUCTION OF 3-AMINO-5-(HYDROXYMETHYL)CYCLOPENTANE-1,2-DIOL DERIVATIVES | LONZA AG (CH) | 2007-04-11 | — | — | EP | disclosed |
| CN-1922166-A | Process for producing 3-amino-5- (hydroxymethyl) cyclopentane-1, 2-diol derivative | LONZA AG (CH) | 2007-02-28 | — | — | CN | disclosed |
| US-6429315-B1 | CYCLIZATION BY REACTION WITH FORMIC ACID DERIVATIVE; DEBLOCKING, DEPROTECTION | AVENTIS PHARMACEUTICALS INC. | 2002-08-06 | — | — | US | disclosed |
| EP-1175420-A2 | PROCESS FOR PREPARING N6-SUBSTITUTED DEAZA-ADENOSINE DERIVATIVES | Aventis Pharmaceuticals Products Inc. (US) | 2002-01-30 | — | — | EP | disclosed |
| EP-1140933-A2 | PROCESS FOR PREPARING N6-SUBSTITUTED DEAZA-ADENOSINE DERIVATIVES | Aventis Pharmacueticals Products Inc. (US) | 2001-10-10 | — | — | EP | disclosed |
| EP-1082120-A1 | PYRROLO[2,3d]PYRIMIDINE COMPOSITIONS AND THEIR USE | OSI Pharmaceuticals, Inc. (US) | 2001-03-14 | — | — | EP | disclosed |
| US-6184382-B1 | 4-(7-((1-((3-CHLOROTHIEN-2-YL)METHYL)PROPYL)AMINO)-3H-IMIDAZO (4, 5-B)PYRID-3-YL) N-ETHYL-2,3-DIHYDROXYCYCLOPENTANECARBOXAMIDE ARE USEFUL AS CARDIOVASCULAR AGENTS, ANTIHYPERTENSIVE, ANTI-ISCHEMIC AGENTS, | AVENTIS PHARMACEUTICALS PRODUCTS INC. | 2001-02-06 | — | — | US | disclosed |
| WO-2000040584-A2 | PROCESS FOR PREPARING N6-SUBSTITUTED DEAZA-ADENOSINE DERIVATIVES | AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) | 2000-07-13 | — | — | WO | disclosed |
| WO-2000037469-A2 | PROCESS FOR PREPARING N6-SUBSTITUTED DEAZA-ADENOSINE DERIVATIVES | AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) | 2000-06-29 | — | — | WO | disclosed |
| WO-1999062518-A1 | PYRROLO[2,3d]PYRIMIDINE COMPOSITIONS AND THEIR USE | OSI PHARMACEUTICALS, INC. (US) | 1999-12-09 | — | — | WO | disclosed |