Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | F13A1 | P00488 | 2/20 | 0.39 |
| ▸ | TGM2 | P21980 | 2/20 | 0.39 |
| ▸ | TGM1 | P22735 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL106354 | 0.83 | USP2 (0.46) | USP2SMN1; SMN2GRM5ESR2EPHX1 | |
| SCHEMBL843458 | 0.83 | USP2 (0.49) | USP2SMN1; SMN2GRM5ESR2EPHX1 | |
| SCHEMBL2948300 | 0.83 | USP2 (0.49) | USP2SMN1; SMN2GRM5ESR2EPHX1 | |
| SCHEMBL14419067 | 0.83 | USP2 (0.49) | USP2SMN1; SMN2GRM5ESR2EPHX1 | |
| SCHEMBL3880705 | 0.82 | SMN1; SMN2 (0.40) | USP2SMN1; SMN2GRM5ESR2EPHX1 | |
| SCHEMBL513310 | 0.81 | GRM5 (0.48) | USP2SMN1; SMN2GRM5ESR2ADORA1 | |
| SCHEMBL24673913 | 0.79 | USP2 (0.51) | USP2SMN1; SMN2GRM5ESR2EPHX1 | |
| SCHEMBL10253506 | 0.79 | USP2 (0.51) | USP2SMN1; SMN2GRM5ESR2EPHX1 | |
| SCHEMBL7603660 | 0.79 | USP2 (0.45) | USP2SMN1; SMN2GRM5ESR2ADORA1 | |
| SCHEMBL3947744 | 0.78 | HPGD (0.43) | USP2SMN1; SMN2GRM5ESR2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117808-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2009-10-01 | — | — | WO | claimed |
| WO-2009117808-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2009-10-01 | — | — | WO | disclosed |