Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2948300 | 0.87 | USP2 (0.49) | USP2SMN1; SMN2GRM5ESR2ADORA1 | |
| SCHEMBL14419067 | 0.87 | USP2 (0.49) | USP2SMN1; SMN2GRM5ESR2ADORA1 | |
| SCHEMBL513310 | 0.85 | GRM5 (0.48) | USP2SMN1; SMN2GRM5ESR2ADORA1 | |
| SCHEMBL106354 | 0.84 | USP2 (0.46) | USP2SMN1; SMN2GRM5ESR2ADORA1 | |
| SCHEMBL24673913 | 0.83 | USP2 (0.51) | USP2SMN1; SMN2GRM5ESR2ADORA1 | |
| SCHEMBL10253506 | 0.83 | USP2 (0.51) | USP2SMN1; SMN2GRM5ESR2ADORA1 | |
| SCHEMBL23748406 | 0.83 | USP2 (0.43) | USP2SMN1; SMN2ESR2MAPTKDM4E | |
| SCHEMBL4078273 | 0.83 | USP2 (0.45) | USP2SMN1; SMN2GRM5ESR2ADORA1 | |
| SCHEMBL7603660 | 0.83 | USP2 (0.45) | USP2SMN1; SMN2GRM5ESR2ADORA1 | |
| SCHEMBL30897992 | 0.81 | USP2 (0.50) | USP2SMN1; SMN2GRM5ESR2ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12590067-B2 | Herbicidal cyclohexanedione derivatives | SYNGENTA CROP PROTECTION AG (CH) | 2026-03-31 | — | — | US | disclosed |
| US-12479804-B2 | Herbicidal compounds | SYNGENTA CROP PROTECTION AG (CH) | 2025-11-25 | — | — | US | disclosed |
| EP-3999492-B1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2025-09-03 | — | — | EP | disclosed |
| US-12281081-B2 | Herbicidal compounds | SYNGENTA CROP PROTECTION AG (CH) | 2025-04-22 | — | — | US | disclosed |
| US-12250947-B2 | Substituted azaspiro-cycles as herbicides | SYNGENTA CROP PROTECTION AG (CH) | 2025-03-18 | — | — | US | disclosed |
| US-20250034170-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2025-01-30 | — | — | US | disclosed |
| EP-3997072-B1 | HERBICIDAL CYCLOHEXANEDIONE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2025-01-22 | — | — | EP | disclosed |
| US-12161115-B2 | Herbicidal compounds | SYNGENTA CROP PROTECTION AG (CH) | 2024-12-10 | — | — | US | disclosed |
| EP-4415706-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | Vanqua Bio, Inc. (US) | 2024-08-21 | — | — | EP | disclosed |
| US-12043599-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2024-07-23 | — | — | US | disclosed |
| US-20030207913-A1 | Azabicyclic-substituted-heteroaryl compounds for the treatment of disease | PHARMACIA & UPJOHN COMPANY | 2003-11-06 | — | — | US | disclosed |
| US-20030176702-A1 | N-(azabicyclo moieties)-substituted hetero-bicyclic aromatic compounds for the treatment of disease | PHARMACIA & UPJOHN COMPANY | 2003-09-18 | — | — | US | disclosed |
| WO-2003072578-A1 | AZABICYCLIC COMPOUNDS WITH ALFA7 NICOTINIC ACETYLCHOLINE RECEPTOR ACTIVITY | PHARMACIA & UPJOHN COMPANY (US) | 2003-09-04 | — | — | WO | disclosed |
| WO-2003070728-A2 | AZABICYCLO-SUBSTITUTED BENZOYLAMIDES AND THIOAMIDES FOR TREATMENT OF CNS-RELATED DISORDERS | PHARMACIA & UPJOHN COMPANY (US) | 2003-08-28 | — | — | WO | disclosed |
| US-20030153595-A1 | Azabicyclic-substituted fused-heteroaryl compounds for the treatment of disease | PHARMACIA & UPJOHN COMPANY | 2003-08-14 | — | — | US | disclosed |
| US-20030130305-A1 | Azabicyclic-phenyl-fused-heterocyclic compounds for treatment of disease | PHARMACIA & UPJOHN COMPANY | 2003-07-10 | — | — | US | disclosed |
| WO-2003040147-A1 | AZABICYCLIC-SUBSTITUTED-HETEROARYL COMPOUNDS FOR THE TREATMENT OF DISEASE__________________________________________________________________________________________________________________________ | PHARMACIA & UPJOHN COMPANY (US) | 2003-05-15 | — | — | WO | disclosed |
| WO-2003037896-A1 | N-AZABICYCLO-SUBSTITUTED HETERO-BICYCLIC CARBOXAMIDES AS NACHR AGONISTS | PHARMACIA & UPJOHN COMPANY (US) | 2003-05-08 | — | — | WO | disclosed |
| WO-2003029252-A1 | AZABICYCLIC-SUBSTITUTED FUSED-HETEROARYL COMPOUNDS FOR THE TREATMENT OF DISEASE | PHARMACIA & UPJOHN COMPANY (US) | 2003-04-10 | — | — | WO | disclosed |
| WO-2002085901-A1 | SUBSTITUTED AZABICYCLIC MOIETIES FOR THE TREATMENT OF DISEASE (NICOTINIC ACETHYLCHOLINE RECEPTOR AGONISTS) | PHARMACIA & UPJOHN COMPANY (US) | 2002-10-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130305-A1 | Azabicyclic-phenyl-fused-heterocyclic compounds for treatment of disease | TPMT, PAICS, MALT1 | USP2 4590/4885SMN1; SMN2 1644/4885GRM5 1786/4885 |
| US-20250034170-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | GBA1, GAA, GBA2 | USP2 2620/4885SMN1; SMN2 159/4885GRM5 556/4885 |
| US-20030153595-A1 | Azabicyclic-substituted fused-heteroaryl compounds for the treatment of disease | MALT1, TPMT, ABCB1 | USP2 4434/4885SMN1; SMN2 1836/4885GRM5 1348/4885 |
| US-12161115-B2 | Herbicidal compounds | DDT, CBR3, GLRX3 | USP2 2225/4885SMN1; SMN2 4743/4885GRM5 220/4885 |
| US-12281081-B2 | Herbicidal compounds | DDT, CBR3, GLRX3 | USP2 2071/4885SMN1; SMN2 4727/4885GRM5 1037/4885 |
| US-20030176702-A1 | N-(azabicyclo moieties)-substituted hetero-bicyclic aromatic compounds for the treatment of disease | CYP1B1, ABCB1, NAT1 | USP2 4765/4885SMN1; SMN2 2389/4885GRM5 2255/4885 |
| US-20030207913-A1 | Azabicyclic-substituted-heteroaryl compounds for the treatment of disease | MALT1, WFS1, NR5A1 | USP2 4261/4885SMN1; SMN2 1751/4885GRM5 596/4885 |
| US-12250947-B2 | Substituted azaspiro-cycles as herbicides | DDT, DHFR, CCNB3 | USP2 2241/4885SMN1; SMN2 4602/4885GRM5 1048/4885 |
| US-12479804-B2 | Herbicidal compounds | DDT, CBR3, CYP4X1 | USP2 1902/4885SMN1; SMN2 4745/4885GRM5 1486/4885 |
| US-12043599-B2 | Herbicidal compounds | DDT, CBR3, GLRX3 | USP2 2071/4885SMN1; SMN2 4727/4885GRM5 1037/4885 |
| US-12590067-B2 | Herbicidal cyclohexanedione derivatives | CBR3, CBR1, OSR1 | USP2 2782/4885SMN1; SMN2 4254/4885GRM5 1306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.