Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | TACR2 | P21452 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SHBG | P04278 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10720837 | 1.00 | TSHR (0.42) | TSHRTHRBPTGS2ESR1ADRA2A | |
| SCHEMBL2550550 | 1.00 | TSHR (0.42) | TSHRTHRBPTGS2ESR1ADRA2A | |
| SCHEMBL28827537 | 1.00 | TSHR (0.42) | TSHRTHRBPTGS2ESR1ADRA2A | |
| SCHEMBL30636884 | 1.00 | TSHR (0.42) | TSHRTHRBPTGS2ESR1ADRA2A | |
| SCHEMBL4873042 | 1.00 | TSHR (0.42) | TSHRTHRBPTGS2ESR1ADRA2A | |
| SCHEMBL6150764 | 1.00 | TSHR (0.42) | TSHRTHRBPTGS2ESR1ADRA2A | |
| SCHEMBL8361095 | 1.00 | TSHR (0.42) | TSHRTHRBPTGS2ESR1ADRA2A | |
| SCHEMBL10719940 | 1.00 | TSHR (0.42) | TSHRTHRBPTGS2ESR1ADRA2A | |
| SCHEMBL7117462 | 1.00 | TSHR (0.42) | TSHRTHRBPTGS2ESR1ADRA2A | |
| SCHEMBL861873 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9388361-B2 | Lubricating oil additive composition and lubricating oil composition | IDEMITSU KOSAN CO., LTD. (JP) | 2016-07-12 | — | — | US | claimed |
| CN-113518613-B | Bio-based pearlescent wax | 巴斯夫欧洲公司 | 2023-12-01 | — | — | CN | disclosed |
| EP-2835414-B1 | USE OF LUBRICATING OIL ADDITIVE COMPOSITION | IDEMITSU KOSAN CO (JP) | 2022-11-30 | — | — | EP | disclosed |
| CN-109689022-B | Low molecular weight keratin hydrolysate | 巴斯夫欧洲公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-113518613-A | Bio-based pearlescent wax | 巴斯夫欧洲公司 | 2021-10-19 | — | — | CN | disclosed |
| CN-109689022-A | Low molecular weight keratin hydrolyzate | 巴斯夫欧洲公司 | 2019-04-26 | — | — | CN | disclosed |
| CN-109689021-A | Protein hydrolysate | 巴斯夫欧洲公司 | 2019-04-26 | — | — | CN | disclosed |
| EP-2829591-B1 | LUBRICANT COMPOSITION FOR INTERNAL COMBUSTION ENGINE OIL | IDEMITSU KOSAN CO (JP) | 2016-11-23 | — | — | EP | disclosed |
| US-9447358-B2 | Lubricant composition for internal combustion engine oil | IDEMITSU KOSAN CO., LTD. (JP) | 2016-09-20 | — | — | US | disclosed |
| US-9388361-B2 | Lubricating oil additive composition and lubricating oil composition | IDEMITSU KOSAN CO., LTD. (JP) | 2016-07-12 | — | — | US | disclosed |
| US-8178701-B2 | Glycerol levulinate ketals and their use | SEGETIS, INC. (US) | 2012-05-15 | — | — | US | disclosed |
| US-20120021962-A1 | GLYCEROL LEVULINATE KETALS AND THEIR USE | SEGETIS, INC. (US) | 2012-01-26 | — | — | US | disclosed |
| US-8053468-B2 | Glycerol levulinate ketals and their use | SEGETIS, INC. (US) | 2011-11-08 | — | — | US | disclosed |
| US-20080242721-A1 | plasticizers; polylactones and polyurethanes prepared from them; substituted oxymethylene moiety attached to the dioxolane ring is predominantly in the cis configuration relative to the configuration of the side chain bearing the carboxyl group | AROMAGEN CORPORATION (US) | 2008-10-02 | — | — | US | disclosed |
| EP-0138559-B1 | KETOALKYLPHOSPHOLIPIDS AND THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1989-08-23 | — | — | EP | disclosed |
| EP-0234377-A1 | Alkyl-substituted 1,6-dihydroxy-3,4-sulfahexanes, process for their preparation and their use | Henkel Kommanditgesellschaft auf Aktien (DE) | 1987-09-02 | — | — | EP | disclosed |
| US-4649203-A | ANTITUMOR, FUNGICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-03-10 | — | — | US | disclosed |
| EP-0138559-A2 | Ketoalkylphospholipids and their production and use | Takeda Chemical Industries, Ltd. (JP) | 1985-04-24 | — | — | EP | disclosed |
| US-4439425-A | IMMUNOLOGY | CIBA-GEIGY CORPORATION (US) | 1984-03-27 | — | — | US | disclosed |
| EP-0014815-A2 | Peptide derivatives, process for their preparation and intermediates, and pharmaceutical compositions containing one of these compounds | CIBA-GEIGY AG (CH) | 1980-09-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242721-A1 | plasticizers; polylactones and polyurethanes prepared from them; substituted oxymethylene moiety attached to the dioxolane ring is predominantly in the cis configuration relative to the configuration of the side chain bearing the carboxyl group | GK, FTO, DGKK | TSHR 4740/4885THRB 4434/4885PTGS2 201/4885 |
| US-20120021962-A1 | GLYCEROL LEVULINATE KETALS AND THEIR USE | GK, GRIK5, KHK | TSHR 4388/4885THRB 4460/4885PTGS2 1052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.